Slc6a2 - solute carrier family 6 member 2 Gene

Also Known as Net

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83511

Summary

Enables alpha-tubulin binding activity; beta-tubulin binding activity; and norepinephrine:sodium symporter activity. Involved in norepinephrine transport and response to xenobiotic stimulus. Located in several cellular components, including cell surface; membrane raft; and neuron projection. Biomarker of mental depression. Human ortholog(s) of this gene implicated in hypertension and neurocirculatory asthenia. Orthologous to human SLC6A2 (solute carrier family 6 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a2 Products (1)

mRNA Protein Name
NM_031343.2 NP_112633.2 sodium-dependent noradrenaline transporter

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables alpha-tubulin binding IDA
IDA: Inferred from direct assay
18800064 RGD
enables beta-tubulin binding IDA
IDA: Inferred from direct assay
18800064 RGD
enables norepinephrine:sodium symporter activity IDA
IDA: Inferred from direct assay
10196144 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
18800064 RGD
Biological Process GO Annotation Evidence References Source
involved in norepinephrine transport IDA
IDA: Inferred from direct assay
10196144 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
18800064 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
14976208 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
10753308 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
10753308 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-dependent noradrenaline transporter

  • NaCl-dependent norepinephrine transporter

  • neurotransmitter transporter, noradrenal

  • norepinephrine transporter

  • solute carrier family 6 (neurotransmitter transporter), member 2

  • solute carrier family 6 (neurotransmitter transporter, noradrenalin), member

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13306 SLC6A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20194 Slc6a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26699 Slc6a2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc6a2 NCBI NCBI:6530