PRSS27 - serine protease 27 Gene

Also Known as MPN; CAPH2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83886

About PRSS27

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:2,712,422-2,720,224 (from NCBI)

This gene has 5 transcripts (splice variants), 123 orthologues and 14 paralogues. Biased expression in esophagus (RPKM 55.3) and skin (RPKM 0.9).

Summary

This gene is located within a large protease gene cluster on chromosome 16. It belongs to the group-1 subfamily of serine proteases. The encoded protein is a secreted tryptic serine protease and is expressed mainly in the pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

PRSS27 Products (2)

mRNA Protein Name
NM_001318395.2 NP_001305324.1 serine protease 27 isoform 2
NM_031948.5 NP_114154.1 serine protease 27 isoform 1 precursor

PRSS27 Protein Structure

Trypsin

Trypsin: Trypsin (36 - 272)

  • 0
  • 100
  • 200
  • 290 a.a.
Protein Preferred Names Protein Names

serine protease 27

  • channel-activating protease 2

Recombinant PRSS27 Proteins

Cat. No. Product Name Accession Purity
HY-P77077 Marapsin/Pancreasin Protein, Human (HEK293, His) Q9BQR3 (A23-K290) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Necrotizing Gastritis
Melnick-Needles Syndrome

  • MNS

  • Melnick-Needles Osteodysplasty

  • Osteodysplasty Of Melnick And Needles

  • Osteochondrodysplasias
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11252 PRSS27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21914 Prss27 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28431 Prss27 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PRSS27 VGNC VGNC:33417
Rattus norvegicus PRSS27 RGD RGD:1303256
Mus musculus PRSS27 MGD MGI:2450123
Felis catus PRSS27 VGNC VGNC:108374
Others PRSS27 NCBI