2. Gene
  3. B3GNT5 - UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 Gene

B3GNT5 - UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as B3GN-T5; beta3Gn-T5

Gene ID: 84002 | Gene type: protein coding

About B3GNT5

Cytogenetic location: 3q27.1 Genomic coordinates (GRCh38): 3:183,253,253-183,273,385 (from NCBI)

This gene has 12 transcripts (splice variants), 250 orthologues and 15 paralogues. Broad expression in bone marrow (RPKM 17.8), small intestine (RPKM 13.8) and 20 other tissues.

Summary

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This Enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This Enzyme is essential for the expression of Lewis X epitopes on glycolipids. [provided by RefSeq, Jul 2008]

B3GNT5 Products(1)

mRNA Protein Name
NM_032047.5 NP_114436.1 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

B3GNT5 Protein Structure

Galactosyl_T

Galactosyl_T: Galactosyltransferase (102 - 299)

  • 0
  • 100
  • 200
  • 300
  • 378 a.a.
Protein Preferred Names Protein Names

lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

BGnT-5

Related Diseases

Diseases Alias
Salt And Pepper Syndrome

Salt & Pepper Syndrome

Salt-And-Pepper Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01312 B3GNT5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus B3GNT5 VGNC VGNC:60057
Macaca mulatta B3GNT5 VGNC VGNC:70077
Canis familiaris B3GNT5 VGNC VGNC:38343
Rattus norvegicus B3GNT5 RGD RGD:70955
Mus musculus B3GNT5 MGD MGI:2137302
Bos taurus B3GNT5 VGNC VGNC:26381