Fads1 - fatty acid desaturase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84575

Summary

Enables acyl-CoA delta5-desaturase activity. Involved in several processes, including response to isolation stress; response to vitamin A; and unsaturated fatty acid metabolic process. Located in nucleus. Biomarker of hypertension and obesity. Orthologous to human FADS1 (fatty acid desaturase 1). [provided by Alliance of Genome Resources, Apr 2022]

Fads1 Products (1)

mRNA Protein Name
NM_053445.2 NP_445897.2 acyl-CoA (8-3)-desaturase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables acyl-CoA delta5-desaturase activity IDA
IDA: Inferred from direct assay
24070791 RGD
enables oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IDA
IDA: Inferred from direct assay
11414679 RGD
Biological Process GO Annotation Evidence References Source
involved in arachidonate metabolic process IMP
IMP: Inferred from mutant phenotype
11414679 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
11841597 RGD
involved in response to insulin IEP
IEP: Inferred from expression pattern
16099631 RGD
involved in response to isolation stress IEP
IEP: Inferred from expression pattern
8115350 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
16333142 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
16099631 RGD
involved in response to sucrose IEP
IEP: Inferred from expression pattern
14506836 RGD
involved in response to vitamin A IEP
IEP: Inferred from expression pattern
11414679 RGD
involved in unsaturated fatty acid biosynthetic process IDA
IDA: Inferred from direct assay
11414679 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acyl-CoA (8-3)-desaturase

  • D5D

  • delta(5) desaturase

  • delta(5) fatty acid desaturase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04666 FADS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-164752 6‑Hydroxy‑FAD / Unkown
HY-RS08852 MUSK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18814 Fads1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25304 Fads1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fads1 NCBI NCBI:3992