RAB27B - Rab27b RAB27B, member RAS oncogene family Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84590

Summary

Predicted to enable several functions, including GTPase activity; guanyl ribonucleotide binding activity; and Myosin V binding activity. Involved in anterograde axonal protein transport; regulation of exocytosis; and synaptic vesicle endocytosis. Located in apical plasma membrane and zymogen granule membrane. Is anchored component of synaptic vesicle membrane. Orthologous to human RAB27B (RAB27B, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

RAB27B Products (1)

mRNA Protein Name
NM_053459.1 NP_445911.1 ras-related protein Rab-27B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15039459 RGD
Biological Process GO Annotation Evidence References Source
involved in anterograde axonal protein transport IMP
IMP: Inferred from mutant phenotype
21775604 RGD
involved in regulation of exocytosis IDA
IDA: Inferred from direct assay
15451418 RGD
involved in synaptic vesicle endocytosis IDA
IDA: Inferred from direct assay
20926670 RGD
involved in synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
20926670 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
17067543 RGD
is active in synaptic vesicle membrane EXP
EXP: Inferred from Experiment
20926670 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
20926670 RGD
located in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
20926670 RGD
located in zymogen granule membrane IDA
IDA: Inferred from direct assay
15451418 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-27B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11538 RAB27B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-184152 IMP-2552 Inhibitor / Unkown
HY-184153 IMP-2958 / Unkown
HY-RS21183 Rab27b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27699 Rab27b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens RAB27B NCBI NCBI:5874