2. Gene
  3. RAB27B - RAB27B, member RAS oncogene family Gene

RAB27B - RAB27B, member RAS oncogene family Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as C25KG

Gene ID: 5874 | Gene type: protein coding

About RAB27B

Cytogenetic location: 18q21.2 Genomic coordinates (GRCh38): 18:54,717,857-54,895,516 (from NCBI)

This gene has 4 transcripts (splice variants), 260 orthologues and 68 paralogues. Biased expression in stomach (RPKM 15.0), prostate (RPKM 9.9) and 13 other tissues.

Summary

Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997 [PubMed 9066979]).[supplied by OMIM, Nov 2010]

RAB27B Products(2)

mRNA Protein Name
NM_001375327.1 NP_001362256.1 ras-related protein Rab-27B
NM_004163.4 NP_004154.2 ras-related protein Rab-27B

RAB27B Protein Structure

Ras

Ras: Ras family (11 - 182)

  • 0
  • 100
  • 200
  • 218 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-27B

Recombinant RAB27B Proteins

Cat. No. Product Name Accession Purity
HY-P75994 RAB27B Protein, Human (HEK293) O00194 (T2-K215) ≥95%
HY-P75995 RAB27B Protein, Human (HEK293, His) O00194 (T2-K215) ≥95%
HY-P75996 RAB27B Protein, Human (HEK293, Fc) O00194 (T2-K215) ≥95%

Related Diseases

Diseases Alias
Griscelli Syndrome

Chediak-Higashi-Like Syndrome

Griscelli-Prunieras Syndrome

Partial Albinism-Immunodeficiency Syndrome

Griscelli Disease

Gs

Hypopigmentation Immunodeficiency Disease

Partial Albinism With Immunodeficiency

Immunodeficiency Syndrome With Hypopigmentation

Hypopigmentation-Immunodeficiency Disease
Piebald Trait

Piebaldism

PBT

Partial Albinism

Albinoidism, Oculocutaneous, Autosomal Dominant
Hermansky-Pudlak Syndrome

Hps

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

Hermanski-Pudlak Syndrome

Hermansky Pudlak Syndrome

Platelet Storage Pool Deficiency
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11538 RAB27B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RAB27B MGD MGI:1931295
Rattus norvegicus RAB27B RGD RGD:620114
Felis catus RAB27B VGNC VGNC:80473
Bos taurus RAB27B VGNC VGNC:33634
Canis familiaris RAB27B VGNC VGNC:45268
Macaca mulatta RAB27B VGNC VGNC:104238
Others RAB27B NCBI