GPRC5A - G protein-coupled receptor class C group 5 member A Gene

Homo sapiens

Also known as RAI3; TIG1; RAIG1; GPCR5A; PEIG-1

Gene ID: 9052 | Gene type: protein coding

About GPRC5A

Cytogenetic location: 12p13.1 Genomic coordinates (GRCh38): 12:12,891,562-12,917,937 (from NCBI)

This gene has 6 transcripts (splice variants), 195 orthologues and 3 paralogues. Biased expression in lung (RPKM 125.2), colon (RPKM 33.4) and 9 other tissues.

Summary

This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq, Jul 2008]

GPRC5A Products(1)

mRNA	Protein	Name
NM_003979.4	NP_003970.1	retinoic acid-induced protein 3

GPRC5A Protein Structure

7tm_3

0
100
200
300
357 a.a.

Protein Preferred Names

Protein Names

retinoic acid-induced protein 3

G-protein coupled receptor family C group 5 member A

Related Diseases

Diseases

Alias

Lung Cancer

Lung Carcinoma	Non-Small Cell Lung Carcinoma
Lung Cancer, Susceptibility To	Lung Cancer, Protection Against
Adenocarcinoma Of Lung, Somatic	Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In
Nonsmall Cell Lung Cancer	Lung Neoplasm
Carcinoma Of Lung	Lung Non-Small Cell Carcinoma
Non-Small Cell Lung Cancer	Nsclc
Lung Neoplasms	Malignant Neoplasm Of Lung
Alveolar Cell Carcinoma	Nonsmall Cell Lung Cancer, Somatic
Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In	Nonsmall Cell Lung Cancer, Susceptibility To
Lung Cancer, Somatic	Lung Cancer, Resistance To
Cancer Of Lung	Cancer Of Bronchus
Cancer Of The Lung	Lung Malignancies
Lung Malignant Tumors	Malignant Lung Tumor
Malignant Tumor Of Lung	Pulmonary Cancer
Pulmonary Carcinoma	Pulmonary Neoplasms
Respiratory Carcinoma	LNCR
Adenocarcinoma Of Lung	Neoplasm Of Lung
Cancer Lung	Carcinoma Non-Small Cell Lung
Carcinoma, Non-Small-Cell Lung	Lung Cancers
Lung Carcinomas	Cancer, Lung
Cancer, Lung, Non-Small Cell	Primary Malignant Neoplasm Of Lung
Bronchioloalveolar Adenocarcinoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-117295A	7-Fluorotryptamine hydrochloride		98.82%	Unkown
HY-RS05749	GPRC5A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	GPRC5A	VGNC	VGNC:73159
Rattus norvegicus	GPRC5A	RGD	RGD:1310804
Canis familiaris	GPRC5A	VGNC	VGNC:41450
Bos taurus	GPRC5A	VGNC	VGNC:29606
Mus musculus	GPRC5A	MGD	MGI:1891250
Felis catus	GPRC5A	VGNC	VGNC:69226

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