7-Fluorotryptamine hydrochloride
Based on 1 Customer Validation
7-Fluorotryptamine hydrochloride is a potent agonist of GPRC5A. 7-Fluorotryptamine hydrochloride induces GPRC5A-mediated β-arrestin recruitment. 7-Fluorotryptamine hydrochloride can be used for research of immune and cancer signaling.
For research use only. We do not sell to patients.
- Purity: 98.87%
- CAS No.: 159730-09-3
- Formula: C10H12ClFN2
- Molecular Weight:214.67
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
GPRC5A[1]
7-Fluorotryptamine (100 μM) hydrochloride induces β-arrestin recruitment by GPRC5A in the PRESTO-Tango assay[1].
7-Fluorotryptamine (50 μM, 8 h) hydrochloride together with TNFα down-regulates some TNFα-induced genes (eg: IL41A, CXCL10, CSF2) in WT and GPRC5A-KO cells[1].
7-Fluorotryptamine (0-100 μM, 16 h) hydrochloride exhibits no toxicity for mammalian cells (HTLA, HT-29 cell)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 159730-09-3
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Appearance Solid
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Molecular Weight 214.67
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Formula C10H12ClFN2
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Color White to off-white
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SMILES
NCCC1=CNC2=C(C=CC=C21)F.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 116.67 mg/mL (543.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.6583 mL | 23.2916 mL | 46.5831 mL | 116.4578 mL |
| 5 mM | 0.9317 mL | 4.6583 mL | 9.3166 mL | 23.2916 mL | |
| 10 mM | 0.4658 mL | 2.3292 mL | 4.6583 mL | 11.6458 mL | |
| 15 mM | 0.3106 mL | 1.5528 mL | 3.1055 mL | 7.7639 mL | |
| 20 mM | 0.2329 mL | 1.1646 mL | 2.3292 mL | 5.8229 mL | |
| 25 mM | 0.1863 mL | 0.9317 mL | 1.8633 mL | 4.6583 mL | |
| 30 mM | 0.1553 mL | 0.7764 mL | 1.5528 mL | 3.8819 mL | |
| 40 mM | 0.1165 mL | 0.5823 mL | 1.1646 mL | 2.9114 mL | |
| 50 mM | 0.0932 mL | 0.4658 mL | 0.9317 mL | 2.3292 mL | |
| 60 mM | 0.0776 mL | 0.3882 mL | 0.7764 mL | 1.9410 mL | |
| 80 mM | 0.0582 mL | 0.2911 mL | 0.5823 mL | 1.4557 mL | |
| 100 mM | 0.0466 mL | 0.2329 mL | 0.4658 mL | 1.1646 mL |
7-Fluorotryptamine hydrochloride Related Classifications
HY-117295A Related Classifications
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