SLC16A6 - solute carrier family 16 member 6 Gene

Also Known as MCT6; MCT7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9120

About SLC16A6

Cytogenetic location: 17q24.2 Genomic coordinates (GRCh38): 17:68,267,026-68,291,479 (from NCBI)

This gene has 4 transcripts (splice variants), 319 orthologues and 13 paralogues. Broad expression in esophagus (RPKM 4.8), appendix (RPKM 3.2) and 18 other tissues.

Summary

Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC16A6 Products (2)

mRNA Protein Name
NM_001174166.2 NP_001167637.1 monocarboxylate transporter 7
NM_004694.5 NP_004685.2 monocarboxylate transporter 7

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC16A6 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (32 - 437)

  • 0
  • 100
  • 200
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  • 500
  • 523 a.a.
Protein Preferred Names Protein Names

monocarboxylate transporter 7

  • breast cancer protein BCY5

SLC16A6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SLC16A6 O15403 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
SLC16A6 O15403 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
SLC16A6 O15403 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13028 SLC16A6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SLC16A6 VGNC VGNC:65213
Macaca mulatta SLC16A6 VGNC VGNC:77399
Rattus norvegicus SLC16A6 RGD RGD:735117
Mus musculus SLC16A6 MGD MGI:2144585
Bos taurus SLC16A6 VGNC VGNC:34692
Canis familiaris SLC16A6 VGNC VGNC:46244
Others SLC16A6 NCBI