CD5L - CD5 molecule like Gene

Also Known as AIM; API6; CT-2; hAIM; PRO229; Spalpha; SP-ALPHA

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 922

About CD5L

Cytogenetic location: 1q23.1 Genomic coordinates (GRCh38): 1:157,827,068-157,841,808 (from NCBI)

This gene has 2 transcripts (splice variants), 371 orthologues and 15 paralogues. Restricted expression toward spleen (RPKM 260.3).

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Predicted to act upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022]

CD5L Products (2)

mRNA Protein Name
NM_001347698.2 NP_001334627.1 CD5 antigen-like isoform 2 precursor
NM_005894.3 NP_005885.1 CD5 antigen-like isoform 1 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
25284781 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CD5L Protein Structure

SRCR

SRCR: Scavenger receptor cysteine-rich domain (27 - 125)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (142 - 239)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (247 - 346)

  • 0
  • 100
  • 200
  • 300
  • 347 a.a.
Protein Preferred Names Protein Names

CD5 antigen-like

  • CD5 antigen-like (scavenger receptor cysteine rich family)

Recombinant CD5L Proteins

Cat. No. Product Name Accession Purity
HY-P72718 CD5L Protein, Human (HEK293, His) O43866 (S20-G347) ≥ 95%, as determined by reducing SDS-PAGE.

CD5L Antibodies

Cat. No. Product Name Application Reactivity
HY-P810149 CD5L Antibody (YA9493) WB, ICC/IF, IF-Tissue, IP, ELISA human

Related Diseases

Diseases Alias
Hereditary Elliptocytosis

  • Congenital Elliptocytosis

  • Ovalocytosis

  • Elliptocytosis, Hereditary

  • He

  • Elliptocytosis Hereditary

  • Congenital Ovalocytosis

  • Elliptocytosis

  • Hereditary Elliptocytosis With Infantile Poikilocytosis

  • Hereditary Ovalocytosis

  • Oval Erythrocytosis

  • He - [Hereditary Elliptocytosis]

  • Elliptocytosis Anaemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS23478 Cd5l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02258 CD5L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17034 Cd5l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CD5L VGNC VGNC:60634
Rattus norvegicus CD5L RGD RGD:1308526
Mus musculus CD5L MGD MGI:1334419
Canis familiaris CD5L VGNC VGNC:38965
Bos taurus CD5L VGNC VGNC:54903
Macaca mulatta CD5L VGNC VGNC:70774
Others CD5L NCBI