B3GNT7 - UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 Gene

Also Known as beta3GnT7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 93010

About B3GNT7

Cytogenetic location: 2q37.1 Genomic coordinates (GRCh38): 2:231,395,710-231,401,164 (from NCBI)

This gene has 2 transcripts (splice variants), 194 orthologues and 15 paralogues. Biased expression in colon (RPKM 27.4), stomach (RPKM 7.8) and 8 other tissues.

Summary

Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]

B3GNT7 Products (1)

mRNA Protein Name
NM_145236.3 NP_660279.1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables acetylglucosaminyltransferase activity IDA
IDA: Inferred from direct assay
17690104 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in keratan sulfate biosynthetic process IDA
IDA: Inferred from direct assay
17690104 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

B3GNT7 Protein Structure

Galactosyl_T

Galactosyl_T: Galactosyltransferase (148 - 343)

  • 0
  • 100
  • 200
  • 300
  • 401 a.a.
Protein Preferred Names Protein Names

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

  • BGnT-7

B3GNT7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
B3GNT7 Q8NFL0 GPR152 Homo sapiens Q8TDT2
Validated Y2H
32296183
Intra
B3GNT7 Q8NFL0 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra
B3GNT7 Q8NFL0 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Macular Dystrophy, Corneal

  • Macular Corneal Dystrophy

  • MCD

  • Corneal Dystrophy, Macular Type

  • Groenouw Type Ii Corneal Dystrophy

  • Fehr Corneal Dystrophy

  • Macular Dystrophy, Corneal Type 1

  • Mcdc1

  • Macular Corneal Dystrophy Type Ii

  • Macular Corneal Dystrophy, Type Ii

  • Macular Corneal Dystrophy, Type I

  • Mcdc1, Formerly

  • Macular Dystrophy, Corneal, 1

  • Macular Corneal Dystrophy Type 1

  • Corneal Dystrophy Groenouw Type Ii

  • Corneal Dystrophy Macular Type

  • Macular Corneal Dystrophy Type I

  • Dystrophy, Macular, Corneal
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With Or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy

  • Catecholaminergic Polymorphic Ventricular Tachycardia 1

  • Ventricular Tachycardia, Catecholaminergic Polymorphic, 1

  • CPVT1

  • Ventricular Tachycardia, Stress-Induced Polymorphic

  • Vtsip

  • Bidirectional Tachycardia

  • Stress-Induced Polymorphic Ventricular Tachycardia

  • Cvpt1

  • Double Tachycardia Induced By Catecholamines

  • Malignant Paroxysmal Ventricular Tachycardia

  • Multifocal Ventricular Premature Beats

  • Paroxysmal Ventricular Fibrillation

  • Syncopal Paroxysmal Tachycardia

  • Syncopal Tachyarythmia

  • Ventricular Tachycardia Catecholaminergic Polymorphic 1

  • Tachycardia, Ventricular, Catecholaminergic Polymorphic, Type 1

  • Multifocal Pvcs

  • Multifocal Premature Ventricular Beats

  • Paroxysmal Familial Ventricular Fibrillation

  • Catecholaminergic Polymorphic Ventricular Tachycardia Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01314 B3GNT7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20528 B3gnt7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27037 B3gnt7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus B3GNT7 MGD MGI:2384394
Felis catus B3GNT7 VGNC VGNC:60059
Canis familiaris B3GNT7 VGNC VGNC:38344
Macaca mulatta B3GNT7 VGNC VGNC:82108
Rattus norvegicus B3GNT7 RGD RGD:1310580
Bos taurus B3GNT7 VGNC VGNC:26383