Gopc - golgi associated PDZ and coiled-coil motif containing Gene

Also Known as CAL; FIG; PIST; GOPC1; 2210402P09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94221

Summary

Enables several functions, including Frizzled binding activity; protein C-terminus binding activity; and protein homodimerization activity. Acts upstream of or within spermatid nucleus differentiation. Located in Golgi apparatus; plasma membrane; and synapse. Is expressed in genitourinary system and tongue. Used to study azoospermia. Orthologous to human GOPC (golgi associated PDZ and coiled-coil motif containing). [provided by Alliance of Genome Resources, Apr 2022]

Gopc Products (2)

mRNA Protein Name
NM_001199272.1 NP_001186201.1 Golgi-associated PDZ and coiled-coil motif-containing protein isoform a
NM_053187.3 NP_444417.2 Golgi-associated PDZ and coiled-coil motif-containing protein isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase regulator activity IDA
IDA: Inferred from direct assay
11162552 MGI
enables frizzled binding IPI
IPI: Inferred from physical interaction
11520064 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11162552 MGI
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
11520064 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within spermatid nucleus differentiation IMP
IMP: Inferred from mutant phenotype
16765935 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
11520064 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
11520064 MGI
located in synapse IDA
IDA: Inferred from direct assay
12372286 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Golgi-associated PDZ and coiled-coil motif-containing protein

  • CFTR-associated ligand

  • PDZ domain-containing protein PIST

  • PDZ protein interacting specifically with TC10

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05599 GOPC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20279 Gopc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26787 Gopc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gopc NCBI NCBI:57120