LY86 - lymphocyte antigen 86 Gene

Also Known as MD1; MD-1; MMD-1; dJ80N2.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9450

About LY86

Cytogenetic location: 6p25.1 Genomic coordinates (GRCh38): 6:6,588,720-6,654,982 (from NCBI)

This gene has 2 transcripts (splice variants) and 130 orthologues. Biased expression in lymph node (RPKM 17.5), spleen (RPKM 16.2) and 13 other tissues.

Summary

Acts upstream of or within positive regulation of lipopolysaccharide-mediated signaling pathway. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

LY86 Products (1)

mRNA Protein Name
NM_004271.4 NP_004262.1 lymphocyte antigen 86 precursor

LY86 Protein Structure

E1_DerP2_DerF2

E1_DerP2_DerF2: ML domain (53 - 159)

  • 0
  • 100
  • 162 a.a.
Protein Preferred Names Protein Names

lymphocyte antigen 86

  • MD-1, RP105-associated

LY86 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
LY86 O95711 GEMIN4 Homo sapiens P57678
Validated Y2H
32296183
Intra
LY86 O95711 GEMIN4 Homo sapiens P57678
Y2H Array
32296183
Intra
LY86 O95711 GEMIN4 Homo sapiens P57678
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant LY86 Proteins

Cat. No. Product Name Accession Purity
HY-P70223 Lymphocyte antigen 86/LY86 Protein, Human (HEK293, Fc) O95711 (G21-S162) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Muscular Dystrophy, Duchenne Type

  • Duchenne Muscular Dystrophy

  • DMD

  • Muscular Dystrophy, Duchenne

  • Muscular Dystrophy, Pseudohypertrophic Progressive, Duchenne Type

  • Severe Dystrophinopathy, Duchenne Type

  • Muscular Dystrophy Duchenne

  • Dystrophy, Muscular, Duchenne Type

  • Benign Duchenne Muscular Dystrophy

  • Duchenne Motor Neuron Disease

  • Duchenne Type Dystrophy

  • Duchenne-Griesinger Disease
Mediastinal Lipomatosis
Myotonic Disease

  • Myotonic Disorders

  • Myotonic Syndrome

  • Symptomatic Myotonia
Frontometaphyseal Dysplasia 1

  • FMD1

  • Fmd
Dilated Cardiomyopathy 1t

  • Cmd1t

  • Cardiomyopathy, Dilated, 1t
Splenic Flexure Cancer

  • Ca Splenic Flexure - Colon

  • Malignant Neoplasm Of Splenic Flexure

  • Malignant Tumor Of Splenic Flexure

  • Malignant Neoplasm Of Splenic Flexure Of Colon
Niemann-Pick Disease, Type C2

  • NPC2

  • Niemann-Pick Disease Type C2

  • Niemann-Pick C2 Disease

  • Niemann-Pick Disease C2
Myotonic Dystrophy 1

  • Myotonic Dystrophy

  • Dystrophia Myotonica

  • Steinert Disease

  • Myotonic Dystrophy Type 1

  • Myotonia Atrophica

  • DM1

  • Congenital Myotonic Dystrophy

  • Myotonia Dystrophica

  • Steinert Myotonic Dystrophy

  • Dystrophia Myotonica 1

  • Dm

  • Steinert'S Disease

  • Steinert Myotonic Dystrophy Syndrome

  • Myotonic Dystrophy Of Steinert

  • Dystrophia Myotonica Type 1

  • Myotonic Dystrophy Congenital

  • Dystrophy, Myotonic, Type 1

  • Dm - [Dystrophia Myotonica]

  • Myotonic Muscular Dystrophy
Gaucher Disease, Type Ii

  • GD2

  • Gd Ii

  • Gaucher Disease, Acute Neuronopathic Type

  • Gaucher Disease Type 2

  • Gaucher Disease Type Ii

  • Gaucher'S Disease Type Ii

  • Infantile Cerebral Gaucher Disease

  • Acute Neuronopathic Gaucher Disease

  • Gd 2

  • Gaucher Disease, Infantile Cerebral

  • Gaucher Disease 2

  • Type 2 Gaucher Disease

  • Gaucher Disease, Type 2
Frontometaphyseal Dysplasia

  • Fmd

  • Dysplasia, Frontometaphyseal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07906 LY86 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19143 Ly86 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25634 Ly86 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus LY86 VGNC VGNC:31093
Rattus norvegicus LY86 RGD RGD:1309936
Canis familiaris LY86 VGNC VGNC:42876
Felis catus LY86 VGNC VGNC:102454
Mus musculus LY86 MGD MGI:1321404
Macaca mulatta LY86 VGNC VGNC:104410
Others LY86 NCBI