Phlpp1 - PH domain and leucine rich repeat protein phosphatase 1 Gene

Also Known as SCOP; Phlpp; Plekhe1; mKIAA0606

Species: Mus musculus

Gene Type: protein coding
Gene ID: 98432

Summary

Predicted to enable protein serine/threonine Phosphatase activity. Involved in regulation of T cell anergy. Acts upstream of or within entrainment of circadian clock. Predicted to be located in nuclear membrane; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in ventricular layer. Orthologous to human PHLPP1 (PH domain and leucine rich repeat protein Phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Phlpp1 Products (1)

mRNA Protein Name
NM_133821.3 NP_598582.3 PH domain leucine-rich repeat-containing protein phosphatase 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within entrainment of circadian clock IMP
IMP: Inferred from mutant phenotype
20080691 MGI
involved in regulation of T cell anergy IMP
IMP: Inferred from mutant phenotype
21498666 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PH domain leucine-rich repeat-containing protein phosphatase 1

  • PH domain-containing family E member 1

  • pleckstrin homology domain containing, family E (with leucine rich repeats) member 1

  • pleckstrin homology domain-containing family E member 1

  • suprachiasmatic nucleus circadian oscillatory protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19820A NSC45586 sodium 98.0% Unkown
HY-19820 NSC45586 / Unkown
HY-RS10447 PHLPP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18428 Phlpp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24909 Phlpp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Phlpp1 NCBI NCBI:23239