Glenthmycin J
Glenthmycin J is a potent antibiotic that can be found in Australian sheep pasture-derived Streptomyces sp. CMB-PB041. Glenthmycin J exhibits activity against Gram-positive bacteria, Methicillin (HY-B0974)-resistant and antibiotic-sensitive Staphylococcus aureus strains. Glenthmycin J can be used for the research of methicillin-resistant Staphylococcus aureus infection and Gram-positive bacterial infections.
For research use only. We do not sell to patients.
- CAS No.: 3040055-89-5
- Formula: C33H44O5
- Molecular Weight:520.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Glenthmycin J (30 μM; 48 h) shows no significant cytotoxicity against human colorectal carcinoma (SW620) or human lung carcinoma (NCI-H460) cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human colorectal carcinoma (SW620), human lung carcinoma (NCI-H460)
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Concentration:30 μM
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Incubation Time:48 h
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Result:Did not exhibit significant cytotoxicity against SW620 or NCI-H460 cells.
Chemical Information
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CAS No. 3040055-89-5
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Molecular Weight 520.71
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Formula C33H44O5
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SMILES
OC=1[C@@]23[C@@](C=C(C)[C@H](C)C2)(/C=C(\C)/CC/C=C(\C)/[C@]4([C@@](C)(C(=O)C1C(=O)O3)[C@]5([C@](C=C4C)([C@@H](O)CC[C@@H]5C)[H])[H])[H])[H]
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Structure Classification
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Initial Source
Streptomyces sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wu T, et al. Glenthmycins A-M: Macrocyclic Spirotetronate Polyketide Antibacterials from the Australian Pasture Plant-Derived Streptomyces sp. CMB-PB041. J Nat Prod. 2022 Jun 24;85(6):1641-1657. [Content Brief]
[2]. Monciardini P, et al. Trends in metabolite discovery from Actinomycetes. Nat Prod Rep. 2025 Sep 17;42(9):1533-1547. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glenthmycin J Related Classifications
HY-N19213 Related Classifications
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