3040055-89-5
Chemical Structure
Glenthmycin J
- CAS No.: 3040055-89-5
- Formula:C33H44O5
- Molecular Weight:520.71
InChIKey: CAGRXMHEDNKEQV-STNOSHSNSA-N
SMILES: OC=1[C@@]23[C@@](C=C(C)[C@H](C)C2)(/C=C(\C)/CC/C=C(\C)/[C@]4([C@@](C)(C(=O)C1C(=O)O3)[C@]5([C@](C=C4C)([C@@H](O)CC[C@@H]5C)[H])[H])[H])[H]
Biological Activity: Glenthmycin J is a potent antibiotic that can be found in Australian sheep pasture-derived Streptomyces sp. CMB-PB041. Glenthmycin J exhibits activity against Gram-positive bacteria, Methicillin (HY-B0974)-resistant and antibiotic-sensitive Staphylococcus aureus strains. Glenthmycin J can be used for the research of methicillin-resistant Staphylococcus aureus infection and Gram-positive bacterial infections[1][2].
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Glenthmycin J | Glenthmycin J is a potent antibiotic that can be found in Australian sheep pasture-derived Streptomyces sp. CMB-PB041. Glenthmycin J exhibits activity against Gram-positive bacteria, Methicillin (HY-B0974)-resistant and antibiotic-sensitive Staphylococcus aureus strains. Glenthmycin J can be used for the research of methicillin-resistant Staphylococcus aureus infection and Gram-positive bacterial infections. | |||||||||||||||||||||
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- [1]. Wu T, et al. Glenthmycins A-M: Macrocyclic Spirotetronate Polyketide Antibacterials from the Australian Pasture Plant-Derived Streptomyces sp. CMB-PB041. J Nat Prod. 2022 Jun 24;85(6):1641-1657. [Content Brief]
- [2]. Monciardini P, et al. Trends in metabolite discovery from Actinomycetes. Nat Prod Rep. 2025 Sep 17;42(9):1533-1547. [Content Brief]
Keywords
