GSK-3β inhibitor 12
Based on 1 Customer Validation
GSK-3β inhibitor 12 (Compound 15) is a GSK-3β inhibitor. GSK-3β inhibitor 12 is applicable to the research of Alzheimer's disease.
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 784170-07-6
- Formula: C14H13N3OS
- Molecular Weight:271.34
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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GSK-3β |
GSK-3β inhibitor 12 (25-50 μM; 30 min) inhibits recombinant hGSK-3β activity, resulting in 49.11% remaining activity at 25 μM and 37.11% remaining activity at 50 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 784170-07-6
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Appearance Solid
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Molecular Weight 271.34
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Formula C14H13N3OS
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Color Light brown to brown
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SMILES
O=C(CC1=CNC2=C1C=CC=C2)NC3=NC=C(C)S3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (460.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.6854 mL | 18.4271 mL | 36.8541 mL | 92.1353 mL |
| 5 mM | 0.7371 mL | 3.6854 mL | 7.3708 mL | 18.4271 mL | |
| 10 mM | 0.3685 mL | 1.8427 mL | 3.6854 mL | 9.2135 mL | |
| 15 mM | 0.2457 mL | 1.2285 mL | 2.4569 mL | 6.1424 mL | |
| 20 mM | 0.1843 mL | 0.9214 mL | 1.8427 mL | 4.6068 mL | |
| 25 mM | 0.1474 mL | 0.7371 mL | 1.4742 mL | 3.6854 mL | |
| 30 mM | 0.1228 mL | 0.6142 mL | 1.2285 mL | 3.0712 mL | |
| 40 mM | 0.0921 mL | 0.4607 mL | 0.9214 mL | 2.3034 mL | |
| 50 mM | 0.0737 mL | 0.3685 mL | 0.7371 mL | 1.8427 mL | |
| 60 mM | 0.0614 mL | 0.3071 mL | 0.6142 mL | 1.5356 mL | |
| 80 mM | 0.0461 mL | 0.2303 mL | 0.4607 mL | 1.1517 mL | |
| 100 mM | 0.0369 mL | 0.1843 mL | 0.3685 mL | 0.9214 mL |
GSK-3β inhibitor 12 Related Classifications
HY-148133 Related Classifications
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