GSK-3β inhibitor 14
Based on 1 publication(s) in Google Scholar
GSK-3β inhibitor 14 (Compound 6i), benzothiazepinone derivative, is a weak GSK-3β inhibitor (IC50 >100 μM).
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 863004-48-2
- Formula: C17H17NOS
- Molecular Weight:283.39
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) GSK-3β inhibitor 14
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Biological Activity
Chemical Information
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CAS No. 863004-48-2
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Appearance Solid
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Molecular Weight 283.39
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Formula C17H17NOS
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Color White to off-white
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SMILES
O=C1CC(C)SC2=CC=CC=C2N1CC3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Mol Med (Berl)
The role and mechanism of TNFRSF21 in promoting necroptosis of vascular endothelial cells and inducing vascular leakage in sepsis. [Abstract]2026 Apr 23;104(1):68. PMID: 42020785
Solvent & Solubility
DMSO : 100 mg/mL (352.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5287 mL | 17.6435 mL | 35.2871 mL | 88.2176 mL |
| 5 mM | 0.7057 mL | 3.5287 mL | 7.0574 mL | 17.6435 mL | |
| 10 mM | 0.3529 mL | 1.7644 mL | 3.5287 mL | 8.8218 mL | |
| 15 mM | 0.2352 mL | 1.1762 mL | 2.3525 mL | 5.8812 mL | |
| 20 mM | 0.1764 mL | 0.8822 mL | 1.7644 mL | 4.4109 mL | |
| 25 mM | 0.1411 mL | 0.7057 mL | 1.4115 mL | 3.5287 mL | |
| 30 mM | 0.1176 mL | 0.5881 mL | 1.1762 mL | 2.9406 mL | |
| 40 mM | 0.0882 mL | 0.4411 mL | 0.8822 mL | 2.2054 mL | |
| 50 mM | 0.0706 mL | 0.3529 mL | 0.7057 mL | 1.7644 mL | |
| 60 mM | 0.0588 mL | 0.2941 mL | 0.5881 mL | 1.4703 mL | |
| 80 mM | 0.0441 mL | 0.2205 mL | 0.4411 mL | 1.1027 mL | |
| 100 mM | 0.0353 mL | 0.1764 mL | 0.3529 mL | 0.8822 mL |
GSK-3β inhibitor 14 Related Classifications
HY-153760 Related Classifications
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