hCAII/IX-IN-1
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with the Kis of 7.4 and 7.0 nM, respectively. hCAII/IX-IN-1 plays an important role in cancer research.
For research use only. We do not sell to patients.
- Formula: C23H22N4O7S2
- Molecular Weight:530.57
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
hCA II 7.4 nM (Ki) |
hCA IX 7 nM (Ki) |
Chemical Information
-
Molecular Weight 530.57
-
Formula C23H22N4O7S2
-
SMILES
OC1=C(OC)C=CC=C1C(C=C(NC2=CC(S(=O)(N)=O)=CC=C2)C3=O)N3C4=CC(S(=O)(N)=O)=CC=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Cristina M Al-Matarneh, et al. Novel 3-Sulfonamide Dual-Tail Pyrrol-2-one Bridged Molecules as Potent Human Carbonic Anhydrase Isoform Inhibitors: Design, Synthesis, Molecular Modeling Investigation, and Anticancer Activity in MeWo, SK-BR-3, and MG-63 Cell Lines. J Med Chem. 2025 Jan 10. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)