TAN-420E
TAN-420E (Dihydroherbimycin A) is an antibiotic, that can be isolated from the fermentation product of Streptomyces hygroscopicus. TAN-420E exhibits cytotoxicity in cancer cells P-388 and KB. TAN-420E scavenges DPPH free radicals with an IC50 of 1.3 μM.
For research use only. We do not sell to patients.
- CAS No.: 91700-93-5
- Formula: C30H44N2O9
- Molecular Weight:576.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| KB | ED50 |
0.3 μg/mL
Compound: 5
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Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 3236008] |
| P388 | ED50 |
0.022 μg/mL
Compound: 5
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Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 3236008] |
Chemical Information
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CAS No. 91700-93-5
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Molecular Weight 576.68
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Formula C30H44N2O9
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SMILES
C[C@H]1C[C@H](OC)[C@H](OC)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(C)\C(NC2=C(O)C([C@@H]1OC)=CC(O)=C2)=O
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Synonyms
Dihydroherbimycin A
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Structure Classification
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Initial Source
Streptomyces hygroscopicus
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)