TEAD-IN-23
TEAD-IN-23 (Compound 22) is an efficient pan-TEAD inhibitor with an IC50 of 10 nM. TEAD-IN-23 exhibits potent anti-proliferative activity in both NCI-H226 and MSTO-211H. TEAD-IN-23 causes complete tumor regression in the MSTO-211H xenograft tumor model. TEAD-IN-23 can be used for the study of mesothelioma and hepatocellular carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 3074990-47-6
- Formula: C23H18ClF3N2O2
- Molecular Weight:446.85
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All YAP Isoforms
More
Biological Activity
|
TEAD 0.01 μM (IC50) |
Chemical Information
-
CAS No. 3074990-47-6
-
Molecular Weight 446.85
-
Formula C23H18ClF3N2O2
-
SMILES
CC1=CC(C2=CN(C3=C2C(Cl)=NC=C3)CCO)=CC(OC4=CC=C(C=C4)C(F)(F)F)=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz