(±)-Eudesmin
(±)-Eudesmin ((±)-Eudesmine) is a natural compound found in Fragaria nubicola with in vitro anti-inflammatory activity. (±)-Eudesmin inhibits NO production in LPS-activated macrophages; suppresses myeloperoxidase-dependent ROS production in zymosan-activated phagocytes; and inhibits superoxide anion production in PMA-activated macrophages. (±)-Eudesmin can be used for the research of inflammation-related diseases.
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- CAS 番号: 25305-05-9
- 分子式: C22H26O6
- 分子量:386.44
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
(±)-Eudesmin (compound 4) moderately inhibits nitric oxide production in LPS-activated J774.2 mouse macrophages, with 29.3% inhibition at 25 µg/mL[1].
(±)-Eudesmin (1-100 µg/mL; 15 min) potently inhibits myeloperoxidase-dependent ROS production in zymosan-activated human peripheral whole blood cells, with an IC50 of 2.3 µg/mL[1].
(±)-Eudesmin (0.5-25 µg/mL; 48 h) is non-cytotoxic to NIH 3T3 mouse fibroblasts, with an IC50 value greater than 25 µg/mL and no toxicity observed at concentrations up to 50 µg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:NIH 3T3 mouse fibroblast cells
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Concentration:0.5, 5, 25 µg/mL
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Incubation Time:48 h
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Result:Showed no cytotoxicity toward NIH 3T3 mouse fibroblasts at concentrations up to 50 µg/mL.
化学情報
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CAS 番号 25305-05-9
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性状 Solid
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分子量 386.44
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分子式 C22H26O6
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Color White to off-white
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SMILES
COC1=CC(C2OCC3C(C4=CC=C(C(OC)=C4)OC)OCC23)=CC=C1OC
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別名
(±)-Eudesmine
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (274 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
(±)-Eudesmin 関連分類
HY-N2180A 関連分類
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