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FAK-IN-22

FAK-IN-22 (Compound 26) is an inhibitor of FAK, JAK3, and Aurora B, with IC50 values of 50.94 nM, 9.99 nM, and 0.49 nM, respectively, effectively inhibiting tumor occurrence and metastasis in pancreatic ductal adenocarcinoma (PDAC). FAK-IN-22 effectively inhibits the proliferation of PANC-1 cells, with an IC50 value of 0.15 μM. FAK-IN-22 induces apoptosis and G2/M phase arrest in PANC-1 cells by inhibiting the FAK/PI3K/Akt signaling pathway.

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  • CAS 番号: 2703920-02-7
  • 分子式: C21H16F3N5O2
  • 分子量:427.38
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • FAK-IN-22 Chemical Structure
    FAK-IN-22 構造式
CAS 番号: 2703920-02-7
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最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

JAK アイソフォーム固有の製品をすべて表示

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Aurora Kinase アイソフォーム固有の製品をすべて表示

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PI3K アイソフォーム固有の製品をすべて表示

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Akt アイソフォーム固有の製品をすべて表示

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100 mg

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  • FAK-IN-22 Chemical Structure
    FAK-IN-22 Chemical Structure
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  • FAK-IN-22