VTA1 - vesicle trafficking 1 Gene

Also Known as DRG1; LIP5; SBP1; DRG-1; My012; 6orf55; C6orf55; HSPC228

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 51534

About VTA1

Cytogenetic location: 6q24.1-q24.2 Genomic coordinates (GRCh38): 6:142,147,263-142,224,685 (from NCBI)

This gene has 5 transcripts (splice variants) and 204 orthologues. Ubiquitous expression in brain (RPKM 16.7), colon (RPKM 13.5) and 25 other tissues.

Summary

C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008]

VTA1 Products (3)

mRNA Protein Name
NM_001286371.2 NP_001273300.1 vacuolar protein sorting-associated protein VTA1 homolog isoform b
NM_001286372.2 NP_001273301.1 vacuolar protein sorting-associated protein VTA1 homolog isoform c
NM_016485.5 NP_057569.2 vacuolar protein sorting-associated protein VTA1 homolog isoform a

VTA1 Protein Structure

Vta1

Vta1: Vta1 like (15 - 177)

Vta1

Vta1: Vta1 like (182 - 303)

  • 0
  • 100
  • 200
  • 307 a.a.
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein VTA1 homolog

  • LYST-interacting protein 5

VTA1 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
VTA1 Q9NP79 CHMP5 Homo sapiens Q9NZZ3
Y2H
16730941
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Arthrogryposis, Distal, Type 1b

  • DA1B

  • Distal Arthrogryposis Type 1b

  • Arthrogryposis, Distal, 1b
Arthrogryposis, Distal, Type 1a

  • Distal Arthrogryposis Type 1

  • Digitotalar Dysmorphism

  • DA1A

  • Da1

  • Amcd1

  • Arthrogryposis, Distal, Type 2b4

  • Distal Arthrogryposis Type 1a

  • Arthrogryposis, Distal, Type 1

  • Arthrogryposis Multiplex Congenita Distal Type 1

  • Arthrogryposis Multiplex Congenita, Distal Type 1

  • Arthrogryposis Multiplex Congenita, Distal, Type I

  • Distal Arthrogryposis Type 1b

  • Arthrogryposis, Distal, 1a

  • Amc

  • Arthrogryposis Multiplex Congenita

  • Arthrogryposis, Distal, 2b4

  • DA2B4

  • Arthrogryposis Multiplex Congenita, Distal, Type 1

  • Arthrogryposis
Meckel Syndrome, Type 6

  • Meckel Syndrome 6

  • MKS6

  • Meckel-Gruber Syndrome, Type 6
Malignant Choroid Melanoma

  • Malignant Melanoma Of Choroid

  • Melanoma Of The Choroid
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-148502 VU6019650 Antagonist 99.83% Unkown
HY-RS15720 VTA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus VTA1 VGNC VGNC:36847
Mus musculus VTA1 MGD MGI:1913451
Felis catus VTA1 VGNC VGNC:66987
Canis familiaris VTA1 VGNC VGNC:48314
Rattus norvegicus VTA1 RGD RGD:1305031
Macaca mulatta VTA1 VGNC VGNC:79296
Others VTA1 NCBI