PPP1CC - protein phosphatase 1 catalytic subunit gamma Gene
Also Known as PP1C; PP-1G; PPP1G
生物種: Homo sapiens
About PPP1CC
This gene has 11 transcripts (splice variants), 231 orthologues and 12 paralogues. Ubiquitous expression in duodenum (RPKM 77.6), small intestine (RPKM 62.4) and 25 other tissues.
Summary
The protein encoded by this gene belongs to the protein Phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine Phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PPP1CC Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001244974.2 | NP_001231903.1 | serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform 2 |
| NM_002710.4 | NP_002701.1 | serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform 1 |
PPP1CC Protein Structure
Metallophos: Calcineurin-like phosphoesterase (59 - 250)
- 0
- 100
- 200
- 300
- 323 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
|
PPP1CC Protein-protein interaction Information
|
Type
|
タンパク質名 | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | 参考文献 |
|---|---|---|---|---|---|---|---|
|
Intra
|
PPP1CC | P36873 | KNL1 | Homo sapiens | Q8NG31 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q13625-3 | 25416956 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q13625-3 | 25416956 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q13625-3 | 25416956 | |
|
Intra
|
PPP1CC | P36873 | PPP1R7 | Homo sapiens | Q15435 | 24366813 | |
|
Intra
|
PPP1CC | P36873 | PPP1R7 | Homo sapiens | Q15435 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | PPP1R7 | Homo sapiens | Q15435 | 23414517 | |
|
Intra
|
PPP1CC | P36873 | PPP1R7 | Homo sapiens | Q15435 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | PPP1R7 | Homo sapiens | Q15435 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | PPP1R2B | Homo sapiens | Q6NXS1 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | PPP1R11 | Homo sapiens | O60927 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | PPP1R11 | Homo sapiens | O60927 | 24366813 | |
|
Intra
|
PPP1CC | P36873 | PPP1R11 | Homo sapiens | O60927 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | PPP1R11 | Homo sapiens | O60927 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | PPP1R2 | Homo sapiens | P41236 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | PPP1R2 | Homo sapiens | P41236 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | PPP1R2 | Homo sapiens | P41236 | 24366813 | |
|
Intra
|
PPP1CC | P36873 | PPP1R2 | Homo sapiens | P41236 | 12761178 | |
|
Intra
|
PPP1CC | P36873 | PPP1R2 | Homo sapiens | P41236 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | PPP1R2 | Homo sapiens | P41236 | 26496610 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q05BL1 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q05BL1 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q05BL1 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | TPRN | Homo sapiens | Q4KMQ1-2 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | TPRN | Homo sapiens | Q4KMQ1-2 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | TPRN | Homo sapiens | Q4KMQ1-2 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | SAXO4 | Homo sapiens | Q7Z5V6-2 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | NRAC | Homo sapiens | Q8N912 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | PPP1R8 | Homo sapiens | Q12972-2 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | PPP1R8 | Homo sapiens | Q12972-2 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | PPP1R8 | Homo sapiens | Q12972-2 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | URI1 | Homo sapiens | O94763-1 | 27505673 | |
|
Intra
|
PPP1CC | P36873 | AATK | Homo sapiens | Q6ZMQ8 | 28065597 | |
|
Intra
|
PPP1CC | P36873 | LMTK2 | Homo sapiens | Q8IWU2 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | LMTK2 | Homo sapiens | Q8IWU2 | 24366813 | |
|
Intra
|
PPP1CC | P36873 | LMTK2 | Homo sapiens | Q8IWU2 | 28065597 | |
|
Intra
|
PPP1CC | P36873 | LMTK2 | Homo sapiens | Q8IWU2 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | LMTK2 | Homo sapiens | Q8IWU2 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | LMTK2 | Homo sapiens | Q8IWU2 | 26496610 | |
|
Intra
|
PPP1CC | P36873 | PPP1R3C | Homo sapiens | Q9UQK1 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | PPP1R3C | Homo sapiens | Q9UQK1 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | PPP1R3C | Homo sapiens | Q9UQK1 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | PPP1R15B | Homo sapiens | Q5SWA1 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | PPP1R15B | Homo sapiens | Q5SWA1 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | PPP1R15B | Homo sapiens | Q5SWA1 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | ZFYVE9 | Homo sapiens | O95405 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | ZFYVE9 | Homo sapiens | O95405 | 25416956 | |
|
Intra
|
PPP1CC | P36873 | ZFYVE9 | Homo sapiens | O95405 | 25416956 | |
|
Intra
|
PPP1CC | P36873 | ZFYVE9 | Homo sapiens | O95405 | 24366813 | |
|
Intra
|
PPP1CC | P36873 | PPP1R9B | Homo sapiens | Q96SB3 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | PPP1R9B | Homo sapiens | Q96SB3 | 25785436 | |
|
Intra
|
PPP1CC | P36873 | PPP1R9B | Homo sapiens | Q96SB3 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | PPP1R9B | Homo sapiens | Q96SB3 | 24366813 | |
|
Intra
|
PPP1CC | P36873 | PPP1R9B | Homo sapiens | Q96SB3 | 26496610 | |
|
Intra
|
PPP1CC | P36873 | PPP1R9B | Homo sapiens | Q96SB3 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | URI1 | Homo sapiens | O94763 | 27505673 | |
|
Intra
|
PPP1CC | P36873 | URI1 | Homo sapiens | O94763 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | URI1 | Homo sapiens | O94763 | 26496610 | |
|
Intra
|
PPP1CC | P36873 | URI1 | Homo sapiens | O94763 | 21397856 | |
|
Intra
|
PPP1CC | P36873 | URI1 | Homo sapiens | O94763 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | URI1 | Homo sapiens | O94763 | 24366813 | |
|
Intra
|
PPP1CC | P36873 | URI1 | Homo sapiens | O94763 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | RRP1B | Homo sapiens | Q14684 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | RRP1B | Homo sapiens | Q14684 | 24366813 | |
|
Intra
|
PPP1CC | P36873 | RRP1B | Homo sapiens | Q14684 | 20926688 | |
|
Intra
|
PPP1CC | P36873 | RRP1B | Homo sapiens | Q14684 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | RRP1B | Homo sapiens | Q14684 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | RRP1B | Homo sapiens | Q14684 | 20926688 | |
|
Intra
|
PPP1CC | P36873 | PPP1R3B | Homo sapiens | Q86XI6 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | PPP1R3B | Homo sapiens | Q86XI6 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | PPP1R3B | Homo sapiens | Q86XI6 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | CSRNP1 | Homo sapiens | Q96S65 | 25416956 | |
|
Intra
|
PPP1CC | P36873 | CSRNP1 | Homo sapiens | Q96S65 | 25416956 | |
|
Intra
|
PPP1CC | P36873 | CSRNP2 | Homo sapiens | Q9H175 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | CSRNP2 | Homo sapiens | Q9H175 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | CSRNP2 | Homo sapiens | Q9H175 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | CSRNP2 | Homo sapiens | Q9H175 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | CSRNP2 | Homo sapiens | Q9H175 | 29892012 | |
|
Intra
|
PPP1CC | P36873 | OGT | Homo sapiens | O15294 | 27505673 | |
|
Intra
|
PPP1CC | P36873 | PPP1R16A | Homo sapiens | Q96I34 | 32296183 | |
|
Intra
|
PPP1CC | P36873 | CD2BP2 | Homo sapiens | O95400 | 25416956 | |
|
Intra
|
PPP1CC | P36873 | CD2BP2 | Homo sapiens | O95400 | 25416956 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q13625 | 33961781 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q13625 | 18448430 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q13625 | 24366813 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q13625 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q13625 | 28330616 | |
|
Intra
|
PPP1CC | P36873 | TP53BP2 | Homo sapiens | Q13625 | 21988832 | |
|
Intra
|
PPP1CC | P36873 | ESR1 | Homo sapiens | P03372 | 17274640 | |
|
Cross
|
PPP1CC | P36873 | Clock | Mus musculus | O08785 | 23555304 | |
|
Intra
|
PPP1CC | P36873 | ZNF629 | Homo sapiens | Q9UEG4 | 32296183 |
Recombinant PPP1CC Proteins
| 製品番号 | 製品名 | アクセッション番号 | 純度 |
|---|---|---|---|
| HY-P71228 | PPP1CC Protein, Human (His) | P36873-1 (M1-K323) | ≥ 85%, as determined by reducing SDS-PAGE. |
PPP1CC 抗体
| 製品番号 | 製品名 | アプリケーション | 反応性 |
|---|---|---|---|
| HY-P81323 | PP1C gamma Antibody (YA1068) | WB | Human |
| HY-P81323A | PP1C gamma Antibody (YA1068)(PBS only) | WB | Human |
| HY-P85518 | PP1C gamma Antibody (YA5210) | WB, IHC-P, FC | Human |
関連疾患
| Diseases | Alias | |
|---|---|---|
| Rheumatoid Arthritis |
|
|
| Rasopathy |
|
|
| Microcephaly |
|
|
| Noonan Syndrome 1 |
|
|
Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Mus musculus | PPP1CC | MGD | MGI:104872 |
| Rattus norvegicus | PPP1CC | RGD | RGD:3377 |
| Bos taurus | PPP1CC | VGNC | VGNC:53916 |
| Canis familiaris | PPP1CC | VGNC | VGNC:52957 |
| Felis catus | PPP1CC | VGNC | VGNC:80466 |
| Others | PPP1CC | NCBI |