2. Gene
  3. PPP1R7 - protein phosphatase 1 regulatory subunit 7 Gene

PPP1R7 - protein phosphatase 1 regulatory subunit 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as SDS22

Gene ID: 5510 | Gene type: protein coding

About PPP1R7

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:241,149,573-241,183,652 (from NCBI)

This gene has 20 transcripts (splice variants), 113 orthologues and 10 paralogues. Broad expression in testis (RPKM 40.9), brain (RPKM 18.7) and 25 other tissues.

Summary

This gene encodes a protein subunit that regulates the activity of the serine/threonine Phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

PPP1R7 Products(7)

mRNA Protein Name
NM_001282409.1 NP_001269338.1 protein phosphatase 1 regulatory subunit 7 isoform 2
NM_001282410.1 NP_001269339.1 protein phosphatase 1 regulatory subunit 7 isoform 3
NM_001282411.1 NP_001269340.1 protein phosphatase 1 regulatory subunit 7 isoform 4
NM_001282412.1 NP_001269341.1 protein phosphatase 1 regulatory subunit 7 isoform 5
NM_001282413.1 NP_001269342.1 protein phosphatase 1 regulatory subunit 7 isoform 6
NM_001282414.1 NP_001269343.1 protein phosphatase 1 regulatory subunit 7 isoform 7
NM_002712.3 NP_002703.1 protein phosphatase 1 regulatory subunit 7 isoform 1

PPP1R7 Protein Structure

LRR_9

LRR_9: Leucine-rich repeat (123 - 213)

LRR_4

LRR_4: Leucine Rich repeats (2 copies) (230 - 272)

LRR_4

LRR_4: Leucine Rich repeats (2 copies) (275 - 315)

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Protein Preferred Names Protein Names

protein phosphatase 1 regulatory subunit 7

protein phosphatase 1 regulatory subunit 22

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11003 PPP1R7 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta PPP1R7 VGNC VGNC:99395
Felis catus PPP1R7 VGNC VGNC:80318
Rattus norvegicus PPP1R7 RGD RGD:1308169
Bos taurus PPP1R7 VGNC VGNC:52808
Canis familiaris PPP1R7 VGNC VGNC:59089
Mus musculus PPP1R7 MGD MGI:1913635
Others PPP1R7 NCBI