Ecm1 - extracellular matrix protein 1 Gene
Also Known as p85
Species: Mus musculus
Gene Type: protein coding
Gene ID: 13601
Summary
Enables interleukin-2 receptor binding activity. Acts upstream of or within several processes, including chondrocyte development; regulation of T cell migration; and regulation of bone mineralization. Located in extracellular space. Is expressed in several structures, including alimentary system; bone; cardiovascular system; skin; and testis. Human ortholog(s) of this gene implicated in lipoid proteinosis. Orthologous to human ECM1 (extracellular Matrix Protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Ecm1 Products (36)
| mRNA | Protein | Name |
|---|---|---|
| NM_001252653.4 | NP_001239582.1 | extracellular matrix protein 1 isoform 2 precursor |
| NM_001355070.3 | NP_001341999.1 | extracellular matrix protein 1 isoform 3 precursor |
| NM_001409917.1 | NP_001396846.1 | extracellular matrix protein 1 isoform 4 precursor |
| NM_001409919.1 | NP_001396848.1 | extracellular matrix protein 1 isoform 5 precursor |
| NM_001409920.1 | NP_001396849.1 | extracellular matrix protein 1 isoform 6 precursor |
| NM_001409921.1 | NP_001396850.1 | extracellular matrix protein 1 isoform 7 precursor |
| NM_001409922.1 | NP_001396851.1 | extracellular matrix protein 1 isoform 8 precursor |
| NM_001409923.1 | NP_001396852.1 | extracellular matrix protein 1 isoform 9 precursor |
| NM_001409924.1 | NP_001396853.1 | extracellular matrix protein 1 isoform 10 precursor |
| NM_001409925.1 | NP_001396854.1 | extracellular matrix protein 1 isoform 11 precursor |
| NM_001409926.1 | NP_001396855.1 | extracellular matrix protein 1 isoform 12 precursor |
| NM_001409927.1 | NP_001396856.1 | extracellular matrix protein 1 isoform 13 precursor |
| NM_001409928.1 | NP_001396857.1 | extracellular matrix protein 1 isoform 14 precursor |
| NM_001409929.1 | NP_001396858.1 | extracellular matrix protein 1 isoform 15 precursor |
| NM_001409930.1 | NP_001396859.1 | extracellular matrix protein 1 isoform 16 precursor |
| NM_001409931.1 | NP_001396860.1 | extracellular matrix protein 1 isoform 17 precursor |
| NM_001409932.1 | NP_001396861.1 | extracellular matrix protein 1 isoform 18 precursor |
| NM_001409933.1 | NP_001396862.1 | extracellular matrix protein 1 isoform 19 precursor |
| NM_001409935.1 | NP_001396864.1 | extracellular matrix protein 1 isoform 20 precursor |
| NM_001409936.1 | NP_001396865.1 | extracellular matrix protein 1 isoform 21 precursor |
| NM_001409938.1 | NP_001396867.1 | extracellular matrix protein 1 isoform 22 precursor |
| NM_001409939.1 | NP_001396868.1 | extracellular matrix protein 1 isoform 23 precursor |
| NM_001409940.1 | NP_001396869.1 | extracellular matrix protein 1 isoform 24 precursor |
| NM_001409941.1 | NP_001396870.1 | extracellular matrix protein 1 isoform 25 precursor |
| NM_001409942.1 | NP_001396871.1 | extracellular matrix protein 1 isoform 26 precursor |
| NM_001409943.1 | NP_001396872.1 | extracellular matrix protein 1 isoform 27 precursor |
| NM_001409944.1 | NP_001396873.1 | extracellular matrix protein 1 isoform 28 precursor |
| NM_001409945.1 | NP_001396874.1 | extracellular matrix protein 1 isoform 29 precursor |
| NM_001409946.1 | NP_001396875.1 | extracellular matrix protein 1 isoform 30 precursor |
| NM_001409947.1 | NP_001396876.1 | extracellular matrix protein 1 isoform 31 precursor |
| NM_001409948.1 | NP_001396877.1 | extracellular matrix protein 1 isoform 32 precursor |
| NM_001409949.1 | NP_001396878.1 | extracellular matrix protein 1 isoform 33 precursor |
| NM_001409950.1 | NP_001396879.1 | extracellular matrix protein 1 isoform 34 precursor |
| NM_001409951.1 | NP_001396880.1 | extracellular matrix protein 1 isoform 35 precursor |
| NM_001409952.1 | NP_001396881.1 | extracellular matrix protein 1 isoform 36 precursor |
| NM_007899.5 | NP_031925.2 | extracellular matrix protein 1 isoform 1 precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables interleukin-2 receptor binding |
IPI
IPI: Inferred from physical interaction
|
21217760 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
20138147 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within chondrocyte development |
IMP
IMP: Inferred from mutant phenotype
|
20138147 | MGI |
| acts upstream of or within endochondral bone growth |
IMP
IMP: Inferred from mutant phenotype
|
20138147 | MGI |
| acts upstream of or within inflammatory response |
IMP
IMP: Inferred from mutant phenotype
|
21217760 | MGI |
| acts upstream of or within negative regulation of cytokine-mediated signaling pathway |
IDA
IDA: Inferred from direct assay
|
21217760 | MGI |
| acts upstream of or within regulation of T cell migration |
IMP
IMP: Inferred from mutant phenotype
|
21217760 | MGI |
| acts upstream of or within regulation of bone mineralization |
IMP
IMP: Inferred from mutant phenotype
|
20138147 | MGI |
| acts upstream of or within regulation of transcription by RNA polymerase II |
IMP
IMP: Inferred from mutant phenotype
|
21217760 | MGI |
| acts upstream of or within regulation of type 2 immune response |
IMP
IMP: Inferred from mutant phenotype
|
21217760 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in extracellular space |
IDA
IDA: Inferred from direct assay
|
7608209 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
extracellular matrix protein 1 |
|
Recombinant Ecm1 Proteins
| Cat. No. | 상품명 | Accession | Purity |
|---|---|---|---|
| HY-P75265 | ECM1 Protein, Mouse (HEK293, His) | Q61508-1 (A20-E559) | ≥ 95%, as determined by reducing SDS-PAGE. |
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(3)
| Cat. No. | 상품명 |
효과
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS04143 | ECM1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS17452 | Ecm1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS23908 | Ecm1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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