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Cat. No.: HY-136878

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LSD1-IN-10

LSD1-IN-10 is a LSD1/MAO inhibitor with LSD1 IC₅₀ of 5 nM, MAO-A IC₅₀ of 16 μM, and MAO-B IC₅₀ of 7.4 μM. LSD1-IN-10 suppresses enzymatic activity of LSD1, MAO-A, and MAO-B. LSD1-IN-10 can be used for the research of cancer, alzheimer's disease, parkinson's disease, huntington's disease.

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CAS No.: 1235864-15-9
화학식: C₁₉H₂₁NO₂
분자량:295.38

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

LSD1-IN-10 Chemical Structure

CAS No.: 1235864-15-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

LSD1

5 nM (IC₅₀)

MAO-A

16 μM (IC₅₀)

MAO-B

7.4 μM (IC₅₀)

All Histone Demethylase Isoforms :

All Monoamine Oxidase Isoforms :

MAO-A
MAO-B

In Vitro

LSD1-IN-10 (Compound 76) potently inhibits LSD1 with an IC₅₀ of 0.005 μM, and is far less potent against MAO-A (IC₅₀ 16 μM) and MAO-B (IC₅₀ 7.4 μM) in cell-free enzymatic assays^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1235864-15-9
분자량 295.38
화학식 C₁₉H₂₁NO₂
SMILES

N(C(C)C=1C=C2C(=CC1)OCCO2)[C@H]3[C@@H](C3)C4=CC=CC=C4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Nathalie G, et al. Phenylcyclopropylamine derivatives and their medical use. United States, WO2010084160 A. 2010-07-29.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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LSD1-IN-10

All Histone Demethylase Isoforms

All Monoamine Oxidase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

LSD1-IN-10 Related Classifications

HY-136878 Related Classifications