Luvometinib-d

(Synonyms: FCN-159-d)

Luvometinib-d (FCN-159-d) is the deuterated-labeled Luvometinib (HY-159846). Luvometinib is an orally potent MEK1/2 inhibitor. Luvometinib selectively blocks the MAPK signaling pathway by forming a ternary complex with MEKase and ATP, thereby reducing the phosphorylation level of ERK. Luvometinib induces cell cycle arrest and apoptosis, and inhibits cancer cell proliferation. Luvometinib can be used in relevant research on various solid tumors including melanoma, non-small cell lung cancer, colon cancer, and acute myeloid leukemia.

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  • 화학식: C26H21DF2IN5O4S
  • 분자량:666.46
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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