YM-750 (Standard)
YM-750 (Standard) is the analytical standard of YM-750 (HY-107396). This product is intended for research and analytical applications. YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 138046-43-2
- 화학식: C31H36N2O
- 분자량:452.63
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocol
- 순도&문서
- References
-
Help & FAQs
-
HY-107396
YM-750ACAT Inhibitor -
HY-107572
PD 128042ACAT/LPAT Inhibitor -
HY-50202A
Etomoxir sodium saltCPT1a Inhibitor -
HY-16706A
Remodelin hydrobromideNAT10 Inhibitor -
HY-13823
C646p300/CBP HAT Inhibitor -
HY-107571
VULM 1457Acyl-CoA Inhibitor -
HY-100400A
K-604 dihydrochlorideACAT1 Inhibitor -
HY-107572R
PD 128042 (Standard)ACAT/LPAT Inhibitor -
HY-B0034
Donepezil HydrochlorideAChE Inhibitor -
HY-107570
IWP-12Acyltransferase Inhibitor -
HY-107569
GarcinolAChE Inhibitor -
HY-124960
CTPBHistone Acetyltransferase Activator
Biological Activity
제품 설명
Chemical Information
-
CAS No. 138046-43-2
-
분자량 452.63
-
화학식 C31H36N2O
-
SMILES
O=C(NC1=C(C)C=C(C)C=C1C)N(C2CCCCCC2)CC3=CC(CC4=C5C=CC=C4)=C5C=C3
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
순도&문서
References
[1]. Nagata Y, et al. N-[2-[N'-pentyl-(6,6-dimethyl-2,4-heptadiynyl)amino]ethyl]- (2-methyl-1-naphthylthio)acetamide (FY-087). A new acyl coenzyme a:cholesterol acyltransferase (ACAT) inhibitor of diet-induced atherosclerosis formation in mice. Biochem Pharmacol. 1995;49(5):643-651. [Content Brief]
[2]. Chang C, et al. Human acyl-CoA:cholesterol acyltransferase (ACAT) and its potential as a target for pharmaceutical intervention against atherosclerosis. Acta Biochim Biophys Sin (Shanghai). 2006;38(3):151-156. [Content Brief]
[3]. Miike T, et al. Effects of an anti-oxidative ACAT inhibitor on apoptosis/necrosis and cholesterol accumulation under oxidative stress in THP-1 cell-derived foam cells. Life Sci. 2008;82(1-2):79-84. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
YM-750 (Standard) Related Classifications
HY-107396R Related Classifications
Powered by Bioz