Linoleic acid alkyne
Based on 1 Customer Validation
Linoleic acid alkyne is an ω-alkyne derivative of Linoleic acid (HY-N0729). Linoleic acid alkyne can be used to synthesize other alkyne-containing products,such as glycerophospholipids, for click chemistry.
For research use only. We do not sell to patients.
- Purity : 96.08%
- CAS No.: 1219038-31-9
- Formula: C18H28O2
- Molecular Weight:276.41
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Storage:
Solution, -20°C, 2 years
Biological Activity
Description
Chemical Information
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CAS No. 1219038-31-9
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Appearance Liquid
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Molecular Weight 276.41
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Formula C18H28O2
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Color Colorless to light yellow
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SMILES
C#CCCC/C=C\C/C=C\CCCCCCCC(O)=O
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Synonyms
ω-Alkynyl linoleic acid
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Protocols
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EdU Incorporation Assay (Click Chemistry-Based DNA Synthesis Measurement)
The EdU incorporation assay measures DNA synthesis by adding the thymidine analog 5-ethynyl-2′-deoxyuridine to cells or tissues, where it is incorporated into newly synthesized DNA during S phase. Incorporated EdU is detected by copper-catalyzed azide-alkyne cycloaddition, in which a fluorescent azide covalently reacts with the ethynyl group on EdU, allowing S-phase cells to be detected by fluorescence microscopy, flow cytometry, or high-content imaging. EdU detection does not require DNA denaturation or anti-BrdU antibody access, which preserves sample structure and improves compatibility with immunostaining and multiparameter cytometry compared with BrdU-based detection. EdU can be cytotoxic in a cell-type- and exposure-dependent manner, so pulse duration, concentration, and continuous-labeling designs should be validated for each cell type.
Purity & Documentation
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Data Sheet (260 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)