Sphingolipids

1-Deoxydihydroceramide is an endogenous chaperone lipid that binds underneath the antigen and pushes the antigen toward the TCR.

EOS (d18:1/32:1/18:2) is a biochemical reagent.

C8 Galactosyl(α) ceramide (d18:1/8:0) is a glycosphingolipid.

C17-Mono-sulfo galactosyl(β) ceramide (d18:1/17:0) ammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

C12 Di-Sulfo galactosyl(β) ceramide (d18:1/12:0) (diammonium) is a glycosphingolipid.

C6 Ceramide-¹³C₂,d₂ (C6-Cer-¹³C₂,d₂) is the deuterium labeled and ¹³C-labeled C6 Ceramide (HY-19542). C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis, inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects.

C22 1-Deoxyceramide (m18:1(14Z)/22:0) (C22 Ceramide (m18:1/22:0); Cer(m18:1/22:0)) is a long-chain ceramide containing a 1-Deoxysphingosine (m18:1(14Z)) (HY-139261).

α-Galactosyl-C16-ceramide (d18:1/16:0) is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

C6 1-Deoxyceramide (m18:1(14Z)/6:0) (Ceramide (m18:1(14Z)/6:0)) is a short-chain ceramide containing a 1-Deoxysphingosine (m18:1(14Z)) (HY-139261).

C6 1-Deoxyceramide (m18:1/6:0) (C6:0 Ceramide (m18:1/6:0)) is a short-chain atypical ceramide.

C6 NBD Sphingomyelin (d18:1/6:0) (NBD SM(d18:1/6:0)) is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). C6 NBD Sphingomyelin (d18:1/6:0) has neutral sphingomyelinase (N-SMase) activity.

C6 NBD L-threo-dihydroceramide is a dihydro-ceramide isomer labeled with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD), can be used to detect ceramide.

C12 NBD Phytoceramide (t18:0/12:0) is a ceramide analogue composed of a phytoceramide and green fluorescent C12 NBD. C12 NBD Phytoceramide (t18:0/12:0) is a fluorescent substrate (Ex=485 nM, Em=525 nM) and can be used to detect ceramidase (such as diacylglycerol acyltransfereases Lro1p) activity.

C12 NBD L-threo Ceramide (d18:1/12:0) (NBD L-threo cer (d18:1/12:0); NBD L-threo ceramide (d18:1/12:0); N-Dodecanoyl-NBD L-threo-sphingosine) is an NBD fluorescently labeled ceramide analog. C12 NBD L-threo Ceramide (d18:1/12:0) is an isomer of C12 NBD ceramide. C12 NBD L-threo Ceramide (d18:1/12:0) can be used for fluorescence detection, imaging, and kinetic analysis.

C12 Lissamine-rhodamine galactosylceramide (d18:1/12:0) (Lissamine-rhodamine B-dodecanoyl Galactosylceramide) is a fluorescently labeled version of C12 galactosylceramide.

N-Hexanoyl-glucosylceramide is an ester product.

N-Hexanoyl-biotin-lactosylceramide is an ester product.

C18:0 Lc4 Ceramide (d18:1/18:0) is a ganglioside.

C18:0 Lc3 Ceramide (d18:1/18:0) is a ganglioside.

C18:0 GD2 Ceramide (d18:1/18:0) is a ganglioside.