- Lipids
- Sphingolipids
- Sphingomyelins
Sphingomyelins
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Sphingomyelins (27)
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- Formula: C35H61N6O9P
- Molecular Weight: 740.87
C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane.
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Sphingomyelins, milk (SMs (buttermilk)) are compounds studied in sphingolipids, which play important roles in various biological processes.
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- Formula: C35H71N2O6P
- Molecular Weight: 646.92
Sphingomyelin (d18:1/12:0) is a metabolomic biomarker. Sphingomyelin (d18:1/12:0) exhibits favorable diagnostic properties and may facilitate the early detection and targeted prevention of dyslipidemia-related adverse cardiovascular events.
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- Formula: C41H73N6O9P
- Molecular Weight: 825.03
C12 NBD sphingomyelin is an active derivative of Sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm).
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- Formula: C41H83N2O6P
- Molecular Weight: 731.08
C18 Sphingomyelin (d18:1/18:0) is a form of sphingomyelin and can be used for study of sphingolipid metabolites.
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- Formula: C41H83N2O6P
- Molecular Weight: 731.08
N-Stearoylsphingomyelin (N-Stearoyl-D-sphingomyelin) is a sphingolipid, which can inhibit Phospholipase Cδ1 (PLCδ1).
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- Formula: C39H81N2O6P
- Molecular Weight: 705.04
N-Palmitoyldihydrosphingomyelin (16:0 Dihydro SM (d18:0/16:0)) is a dihydrosphingomyelin.
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- Formula: C47H93N2O6P
- Molecular Weight: 813.22
N-Nervonoyl-D-erythro-sphingosylphosphorylcholine is a biochemical reagent.
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- Formula: C23H49N2O5P
- Molecular Weight: 464.62
L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is an endogenous bioactive sphingolipid. L-threo Lysosphingomyelin (d18:1) is a potent S1P receptor agonist with EC50s of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively.
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- Formula: C43H85N2O6P
- Molecular Weight: 757.12
C20 Sphingomyelin (d18:1/20:1) is a sphingomyelin substance. The level of C20 Sphingomyelin (d18:1/20:1) is associated with amyotrophic lateral sclerosis and primary lateral sclerosis.
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- Formula: C45H91N2O6P
- Molecular Weight: 787.19
N-Docosanoyl-D-erythro-sphingosylphosphorylcholine (Sphingomyelin (d18:1 C22:0)) is a compound that appears in the plasma sphingolipid profile after chronic hepatitis C virus infection. The level of this substance in plasma is associated with hepatic steatosis and may be an independent factor of hepatic steatosis.
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- Formula: C37H75N2O6P
- Molecular Weight: 674.97
Sphingomyelin (d18:1,C14:0), a major sphingolipid in mammalian cells, increases membrane molecular order.
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- Formula: C40H81N2O6P
- Molecular Weight: 717.05
C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
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- Formula: C38H77N2O6P
- Molecular Weight: 689.00
SM (d18:1/15:0) is a sphingomyelinase inhibitor. SM (d18:1/15:0) is promising for research of neurodegenerative diseases (e.g., Alzheimer's) and metabolic syndrome.
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- Formula: C37H77N2O6P
- Molecular Weight: 676.99
14:0 Dihydro SM (d18:0/14:0) is a sphingomyelin.
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- Formula: C43H87N2O6P
- Molecular Weight: 759.13
C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0)) is a naturally occurring sphingolipid. C20 Sphingomyelin (d18:1/20:0) levels are upregulated in the hippocampus of streptozotocin (HY-13753)-induced diabetic rats and in human plasma, positively correlating with insulin resistance in obese humans. C20 Sphingomyelin (d18:1/20:0) is also upregulated in the liver of a mouse model of Niemann-Pick C1 disease, a neurodegenerative cholesterol sphingolipid lysosomal storage disorder.
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- Formula: C41H81N2O6P
- Molecular Weight: 729.08
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- Formula: C45H93N2O6P
- Molecular Weight: 789.22
CerPCho (d18:0/22:0) is a sphingomyelin with a d18:0-type sphingosine long-chain base and a 22:0-type N-acyl fatty acid.
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- Formula: C51H103N2O6P
- Molecular Weight: 871.35
28:0 SM (d18:1/28:0) is a lycerophospholipid.
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