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Cat. No.: HY-135140

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Methyltetrazine-amine

Name: Methyltetrazine-amine
Brand: MedChemExpress
SKU: HY-135140
Price: 30.00 USD
Availability: InStock
Rating: 5 (1 reviews)

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Methyltetrazine-amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates.

For research use only. We do not sell to patients.

Purity : 99.36%
CAS No.: 1345955-28-3
Formula: C₁₀H₁₁N₅
Molecular Weight:201.23

Storage:

4°C, protect from light

* The compound is unstable in solutions, freshly prepared is recommended.

Methyltetrazine-amine Chemical Structure

CAS No.: 1345955-28-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Methyltetrazine-amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates^[1].

In Vitro

Methyltetrazine-amine is widely used in click chemistry, especially in the inverse electron demand Diels-Alder (iEDDA) click reaction. Methyltetrazine-amine can undergo iEDDA click reaction with hydrogel containing Norbornene (HY-W013021) to form injectable scaffold materials, which can be used for tissue engineering^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 1345955-28-3
Appearance Solid
Molecular Weight 201.23
Formula C₁₀H₁₁N₅
Color Purple to purplish red
SMILES

NCC1=CC=C(C2=NN=C(C)N=N2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

* The compound is unstable in solutions, freshly prepared is recommended.

Publications (1)

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Journal Impact Factor

bioRxiv

2026 May 29.

Solvent & Solubility

In Vitro:

DMSO : 20 mg/mL (99.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

1 M HCl : 4 mg/mL (19.88 mM; ultrasonic and warming and adjust pH to 1 with 1 M HCL and heat to 60°C)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

4.9694 mL

24.8472 mL

49.6944 mL

5 mM

0.9939 mL

4.9694 mL

9.9389 mL

10 mM

0.4969 mL

2.4847 mL

4.9694 mL

Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Dilution Calculator

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Antoine Maruani, et al. A Plug-and-Play Approach for the De Novo Generation of Dually Functionalized Bispecifics. Bioconjug Chem. 2020 Mar 18;31(3):520-529. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
1 M HCl / DMSO	1 mM	4.9694 mL	24.8472 mL	49.6944 mL	124.2360 mL
	5 mM	0.9939 mL	4.9694 mL	9.9389 mL	24.8472 mL
	10 mM	0.4969 mL	2.4847 mL	4.9694 mL	12.4236 mL
	15 mM	0.3313 mL	1.6565 mL	3.3130 mL	8.2824 mL
DMSO	20 mM	0.2485 mL	1.2424 mL	2.4847 mL	6.2118 mL
	25 mM	0.1988 mL	0.9939 mL	1.9878 mL	4.9694 mL
	30 mM	0.1656 mL	0.8282 mL	1.6565 mL	4.1412 mL
	40 mM	0.1242 mL	0.6212 mL	1.2424 mL	3.1059 mL
	50 mM	0.0994 mL	0.4969 mL	0.9939 mL	2.4847 mL
	60 mM	0.0828 mL	0.4141 mL	0.8282 mL	2.0706 mL
	80 mM	0.0621 mL	0.3106 mL	0.6212 mL	1.5529 mL

Bioz

Keywords

Methyltetrazine-amine

1 Cited Publications

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Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Solvent & Solubility
- In Vitro
Purity & Documentation
References

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Methyltetrazine-amine

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