Muscarinic toxin 3
Muscarinic toxin 3 (MT3) is a potent and non-competitive mAChR and adrenoceptors antagonist with pIC50s of 6.71, 8.79, 8.86, 7.57, 8.13, 8.49, <6.5, 7.29 against M1, M4, α1A, α1B, α1D,α2A,α2B and α2C receptors, respectively. Muscarinic toxin 3 displays prominent adrenoceptor activity.
For research use only. We do not sell to patients.
- CAS No.: 873336-87-9
- Formula: C319H489N89O97S8
- Molecular Weight:7379.35
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Adrenergic Receptor Isoforms
More
Biological Activity
pIC50: 8.79 (M4 mAChR), 6.71 (M1 mAChR), 8.86 (α1A-adrenoceptor), 8.49 (α2A-adrenoceptor), 8.13 (α1D-adrenoceptor), 7.57 (α1B-adrenoceptor), 7.29 (α2C-adrenoceptor), <6.5 (α2B-adrenoceptor)[1]
Chemical Information
-
CAS No. 873336-87-9
-
Molecular Weight 7379.35
-
Formula C319H489N89O97S8
-
Synonyms
MT3
-
Sequence
Leu-Thr-Cys-Val-Thr-Lys-Asn-Thr-Ile-Phe-Gly-Ile-Thr-Thr-Glu-Asn-Cys-Pro-Ala-Gly-Gln-Asn-Leu-Cys-Phe-Lys-Arg-Trp-His-Tyr-Val-Ile-Pro-Arg-Tyr-Thr-Glu-Ile-Thr-Arg-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Ile-Pro-Glu-Asn-Tyr-Asp-Ser-Ile-His-Cys-Cys-Lys-Thr-Asp-Lys-Cys-Asn-Glu (Disulfide bridge: Cys3-Cys24,Cys17-Cys42,Cys46-Cys57,Cys58-Cys63)
-
Sequence Shortening
LTCVTKNTIFGITTENCPAGQNLCFKRWHYVIPRYTEITRGCAATCPIPENYDSIHCCKTDKCNE (Disulfide bridge: Cys3-Cys24,Cys17-Cys42,Cys46-Cys57,Cys58-Cys63)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Muscarinic toxin 3 Related Classifications
HY-P5846 Related Classifications
Powered by Bioz