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NRL-1049 dihydrochloride

(Synonyms: BA-1049)
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NRL-1049 dihydrochloride (BA-1049) is a selective and orally active rho-associated protein kinase 2 (ROCK2) inhibitor with an IC50 of 0.59 μM. NRL-1049 dihydrochloride shows selectivity for ROCK2 is 44 times that of ROCK1 (IC50 = 26 μM). NRL-1049 dihydrochloride can preserve the blood-brain barrier after acute injury.

For research use only. We do not sell to patients.

  • Purity: 99.20%
  • CAS No.: 1973494-17-5
  • Formula: C16H23Cl2N3O2S
  • Molecular Weight:392.34
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • NRL-1049 dihydrochloride Chemical Structure
    NRL-1049 dihydrochloride Chemical Structure
CAS No.: 1973494-17-5
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All ROCK Isoforms

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  • NRL-1049 dihydrochloride Chemical Structure
    NRL-1049 dihydrochloride Chemical Structure
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  • NRL-1049 dihydrochloride