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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6968 Results for "
factor
" in MedChemExpress (MCE) Product Catalog:
Products (6968)
6968 Results for "factor" in MCE Product Catalog:
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Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor being developed for the treatment of anemia associated with chronic kidney disease.
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Category:
Plants Endogenous metabolite Human Gut Microbiota Metabolites other families Monophenols Sunscreen Simple Phenylpropanols Phenols Cosmetic Research Phenylpropanoids Disease Research Fields Cancer
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19 Cited Publications
Cat. No.: HY-B0441
CAS No.: 32986-56-4
Synonyms: Nebramycin factor 6; Deoxykanamycin B
Category:
Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
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19 Cited Publications
Cat. No.: HY-B0441A
CAS No.: 49842-07-1
Synonyms: Nebramycin factor 6 sulfate; Deoxykanamycin B sulfate
Category:
Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
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19
19 Cited Publications
Cat. No.: HY-P7110A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VEGFA; Vascular Endothelial Growth factor A; VEGF; VPF; Vascular Permeability factor; Vascular Endothelial Growth factor A, Long Form; VEGF-A; L-VEGF; Vascular Endothelial Growth factor A121; Vascular Endothelial Growth factor A165; Vascular Endothelial G
Species:
Human
Source:
HEK293
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19 Cited Publications
Cat. No.: HY-N0279
CAS No.: 18956-16-6
Synonyms: Cardamomin; Alpinetin chalcone
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Nafamostat mesylate (FUT-175), an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat mesylate has anticancer and antivirus effect. Nafamostat mesylate induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). Nafamostat mesylate can be used in the development of the pathological thickening of the arterial wall .
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18 Cited Publications
Cat. No.: HY-P7425
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; Tumor Necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor Kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor Kappa B Ligand; OPGL; Tumor Necrosis factor Ligand Superfamily Member; ODF; Tumor Necrosis factor Superfamily Member 11; Tumor Necrosis factor Ligand Superfamily Member 11; Tumor Necrosis factor Ligand 6B; TNF-Related Activation-Induced Cytokine; CD254 Antigen; Osteoclast Differentiation factor; HRANKL2; Osteoprotegerin Ligand; OPTB2; CD254; SOdf
Species:
Mouse
Source:
E. coli
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Amifostine (WR2721) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine protects cells from damage by scavenging oxygen-derived free radicals. Amifostine reduces renal toxicity and has antiangiogenic action .
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Amifostine trihydrate (WR2721 trihydrate) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine trihydrate selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine trihydrate is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine trihydrate protects cells from damage by scavenging oxygen-derived free radicals. Amifostine trihydrate reduces renal toxicity and has antiangiogenic action .
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MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29 μM in human vitro. MKC8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC50 of 0.52 μM and unstresses RPMI 8226 cells with an IC50 of 0.14 μM . MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibits prostate cancer (PCa) tumor growth .
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16 Cited Publications
Synonyms: S-Farnesylthiosalicylic acid; Farnesyl Thiosalicylic Acid; FTS
Salirasib is a Ras inhibitor that inhibits specifically both oncogenically activated Ras and growth factor receptor-mediated Ras activation, resulting in the inhibition of Ras-dependent tumor growth.
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Rivaroxaban (BAY 59-7939) is a highly potent, selective and direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
