32986-56-4
Chemical Structure
Tobramycin
Synonym(s): Nebramycin Factor 6; Deoxykanamycin B
- CAS No.: 32986-56-4
- Formula:C18H37N5O9
- Molecular Weight:467.51
IUPAC Name: (2S,3R,4S,5S,6R)-4-amino-2-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol
InChIKey: NLVFBUXFDBBNBW-PBSUHMDJSA-N
SMILES: O[C@@H]([C@@H]1O[C@@]([C@@H](C[C@@H]2O)N)([H])O[C@@H]2CN)[C@H]([C@@H](C[C@@H]1N)N)O[C@@]([C@@H]([C@@H](N)[C@@H]3O)O)([H])O[C@@H]3CO
Biological Activity: Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms[1].Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa[2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Tobramycin | 99.93% | Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms.Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Tobramycin (Standard) | ≥98% | Tobramycin (Standard) is the analytical standard of Tobramycin. This product is intended for research and analytical applications. Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms.Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.93
HY-B0441BTobramycin monosulfate -
Similarity Score 0.87
HY-B1174RBekanamycin (Standard) -
Similarity Score 0.86
HY-Z16210Nebramycin Ⅴ’ -
Similarity Score 0.85
HY-16566Kanamycin -
Similarity Score 0.82
HY-B1174ABekanamycin sulfate -
Similarity Score 0.81
HY-1803283''-Deamino-3''-hydroxykanamycin B -
Similarity Score 0.80
HY-16566ARKanamycin sulfate (Standard) -
Similarity Score 0.77
HY-N14485Nebramycin Ⅳ -
Similarity Score 0.77
HY-N13959Seldomycin factor 1 -
Explore the MedChemAI to find more analogs
References
- [1]. Tobramycin. [Content Brief]
- [2]. VanDrisse CM, et.al. Computationally designed pyocyanin demethylase acts synergistically with tobramycin to kill recalcitrant Pseudomonas aeruginosa biofilms. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2022012118. [Content Brief]
- [3]. Louie A, et.al. Impact of meropenem in combination with tobramycin in a murine model of Pseudomonas aeruginosa pneumonia. Antimicrob Agents Chemother. 2013 Jun;57(6):2788-92. [Content Brief]
