Oxybutynin-d11 chloride
Based on 1 Customer Validation
Oxybutynin-d11 (chloride) is the deuterium labeled Oxybutynin chloride. Oxybutynin chloride is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM.
For research use only. We do not sell to patients.
- Purity: 97.39%
- CAS No.: 1185151-95-4
- Formula: C22H21D11ClNO3
- Molecular Weight:405.02
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 1185151-95-4
-
Unlabeled Cas 1508-65-2
-
Appearance Solid
-
Molecular Weight 405.02
-
Formula C22H21D11ClNO3
-
Color White to off-white
-
SMILES
CCN(CC)CC#CCOC(C(C1([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H])(C2=CC=CC=C2)O)=O.Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (246.90 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Li H, The anticholinergic drug oxybutynin inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells. Clin Exp Pharmacol Physiol. 2019 Nov;46(11):1030-1036. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4690 mL | 12.3451 mL | 24.6901 mL | 61.7253 mL |
| 5 mM | 0.4938 mL | 2.4690 mL | 4.9380 mL | 12.3451 mL | |
| 10 mM | 0.2469 mL | 1.2345 mL | 2.4690 mL | 6.1725 mL | |
| 15 mM | 0.1646 mL | 0.8230 mL | 1.6460 mL | 4.1150 mL | |
| 20 mM | 0.1235 mL | 0.6173 mL | 1.2345 mL | 3.0863 mL | |
| 25 mM | 0.0988 mL | 0.4938 mL | 0.9876 mL | 2.4690 mL | |
| 30 mM | 0.0823 mL | 0.4115 mL | 0.8230 mL | 2.0575 mL | |
| 40 mM | 0.0617 mL | 0.3086 mL | 0.6173 mL | 1.5431 mL | |
| 50 mM | 0.0494 mL | 0.2469 mL | 0.4938 mL | 1.2345 mL | |
| 60 mM | 0.0412 mL | 0.2058 mL | 0.4115 mL | 1.0288 mL | |
| 80 mM | 0.0309 mL | 0.1543 mL | 0.3086 mL | 0.7716 mL | |
| 100 mM | 0.0247 mL | 0.1235 mL | 0.2469 mL | 0.6173 mL |
Oxybutynin-d11 chloride Related Classifications
HY-B0267AS Related Classifications
Powered by Bioz