Protein kinase inhibitor 1
Based on 4 publication(s) in Google Scholar
Protein kinase inhibitor 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
For research use only. We do not sell to patients.
- CAS No.: 1365986-44-2
- Formula: C18H17N5O3S
- Molecular Weight:383.42
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) Protein kinase inhibitor 1
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Biological Activity
Chemical Information
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CAS No. 1365986-44-2
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Appearance Solid
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Molecular Weight 383.42
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Formula C18H17N5O3S
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Color Light yellow to yellow
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SMILES
O=C(NC/1=O)SC1=C\C2=CNC(C(C3=CC=C(N4CCNCC4)N=C3)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (4)
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Journal Impact Factor
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Most Recent
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EBioMedicine
2022 Nov:85:104274. PMID: 36182775 -
EBioMedicine
Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction. [Abstract]2021 Dec:74:103713. PMID: 34837851 -
Biol Direct
Phosphorylation-stabilized CRTC1 cooperates with CBP and androgen receptor to transactivate AMH expression and drive polycystic ovary syndrome. [Abstract]2025 Jun 19;20(1):71. PMID: 40537816 -
J Biochem Mol Toxicol
Homocysteine induced a calcium-mediated disruption of mitochondrial function and dynamics in endothelial cells. [Abstract]2021 May;35(5):e22737. PMID: 33751715
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)