1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands

  • Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11. doi: 10.1016/j.bmcl.2005.01.031.
Mase Lee  1 ,  Jagadeesh B Rangisetty ,  Manik R Pullagurla ,  Małgorzata Dukat ,  Vince Setola ,  Bryan L Roth ,  Richard A Glennon
Affiliations
  • 1. Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298-0540, USA.
PMID: 15745826 DOI: 10.1016/j.bmcl.2005.01.031
Abstract

4-Sulfonyl analogs of 1-(1-naphthyl)piperazine bind at human 5-HT6 receptors and represent a novel class of human 5-HT6 receptor ligands.

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