Acceleration of lipid degradation by sericoside of Terminalia sericea roots in Fully differentiated 3T3-L1 cells

Sericoside is a traditional herbal saponin from Terminalia sericea (Family Combretaceae). The influence of sericoside on lipolysis was studied in fully differentiated 3T3-L1 cells, and glycerol release into the cytosol and residual triglyceride were measured. The addition of sericoside stimulated glycerol release into the cytosol from deposited triglyceride in a dose- and time-dependent manner. These data suggested that sericoside has a strong lipolytic activity.