Justicisaponin-I, a new triterpenoid saponin from Justicia simplex

  • Planta Med. 1981 Jul;42(7):279-83. doi: 10.1055/s-2007-971641.
S Ghosal  1 ,  A K Srivastava ,  R S Srivastava ,  S Chattopadhyay ,  M Maitra
Affiliations
  • 1. Department of Pharmaceutics, Banaras Hindu University, Varanasi-5.
PMID: 17401975 DOI: 10.1055/s-2007-971641
Abstract

A new triterpenoid saponin, named justicisaponin-I, has been isolated from Justicia simplex D. Don. (Acanthaceae). It has been assigned oleanolic acid-3-O-beta-D-glucopyranosyl-4'-O-ferulate structure (1) on the basis of chemical transformation and comprehensive spectral evidence. Justicisaponin-I has produced significant sperm acrosomal membrane stabilizing action and may prove to be a potent antifertility agent.

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