Caffeic acid derivatives from Eupatorium perfoliatum L

  • Molecules. 2008 Dec 23;14(1):36-45. doi: 10.3390/molecules14010036.
Mareike Maas  1 ,  Frank Petereit ,  Andreas Hensel
Affiliations
  • 1. University of Münster, Institute for Pharmaceutical Biology and Phytochemistry, Hittorfstrasse 56, D-48149 Münster, Germany.
PMID: 19104484 DOI: 10.3390/molecules14010036
Abstract

From the ethyl acetate soluble fraction of a methanol/water extract of the herb Eupatorium perfoliatum L. (Asteraceae) six caffeic acid derivatives have been isolated and identified by 1D- and 2D-NMR spectroscopic data. Besides the common quinic acid derivatives 5-caffeoylquinic acid (chlorogenic acid), 3-caffeoylquinic acid (neochlorogenic acid) and 3,5-dicaffeoylquinic acid, three up to now unknown depsides of caffeic acid with glucaric acid have been isolated: 2,5-dicaffeoylglucaric acid, 3,4-dicaffeoylglucaric acid, and 2,4- or 3,5-dicaffeoylglucaric acid.

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