New insights into Whipple's disease and Tropheryma whipplei infections

  • Microbes Infect. 2010 Dec;12(14-15):1102-10. doi: 10.1016/j.micinf.2010.08.001.
Benoit Desnues  1 ,  Khatoun Al Moussawi ,  Florence Fenollar
Affiliations
  • 1. URMITE, CNRS-IRD UMR 6236, Université de la Méditerranée, Faculté de Médecine de la Timone, 27 Boulevard Jean Moulin, 13385 Cedex 5 Marseille, France. [email protected]
PMID: 20708091 DOI: 10.1016/j.micinf.2010.08.001
Abstract

Whipple's disease is a rare multi-systemic disease associated with the ubiquitous environmental bacterium Tropheryma whipplei. Over the last 10 years, since the isolation of the bacterium, recent advances in medical microbiology, epidemiology and cellular biology have provided major insights into the understanding of the pathophysiology of T. whipplei infections that may result in Whipple's disease.