Comparative analysis of Candida biofilm quantitation assays

  • Med Mycol. 2012 Feb;50(2):214-8. doi: 10.3109/13693786.2011.580016.
Heather T Taff  1 ,  Jeniel E Nett ,  David R Andes
Affiliations
  • 1. Department of Microbiology and Immunology, University of Wisconsin, Wisconsin, USA.
PMID: 21539503 DOI: 10.3109/13693786.2011.580016
Abstract

Candida grows on devices producing treatment resistant biofilms. A key tool for the study of biofilms includes an accurate assessment of viable cell growth. This study systematically tested seven techniques, among which the XTT assay provided the most reproducible, accurate, and efficient method for the quantitative estimation of C. albicans biofilms.