Myrseguinosides A-E, five new glycosides from the fruits of Myrsine seguinii

  • Chem Pharm Bull (Tokyo). 2011;59(10):1274-80. doi: 10.1248/cpb.59.1274.
Katsuyoshi Matsunami  1 ,  Hideaki Otsuka ,  Yoshio Takeda
Affiliations
  • 1. Department of Pharmacognosy, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
PMID: 21963638 DOI: 10.1248/cpb.59.1274
Abstract

Chemical investigation of the 1-BuOH soluble fraction of the dried fruits of Myrsine seguinii (Myrsinaceae) led to the isolation of five new glycosides, named myrseguinosides A-E (1-5), together with eight known compounds (6-13). The absolute structures of the new glycosides were elucidated by spectroscopic and chemical analyses to be a monoterpene glucoside (1), two flavonol glycosides (2, 3), and two oleanane-type triterpene saponins (4, 5). Myrseguinosides B (2), D (4), and E (5) exhibited 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity and growth inhibitory activity toward human Cancer cells, respectively.

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