Antimicrobial constituents from the tubers of Bletilla ochracea

  • Planta Med. 2012 Apr;78(6):606-10. doi: 10.1055/s-0031-1298264.
Xinzhou Yang  1 ,  Chunping Tang ,  Ping Zhao ,  Guangwen Shu ,  Zhinan Mei
Affiliations
  • 1. College of Pharmacy, South-Central University for Nationalities, Wuhan, P. R. China.
PMID: 22383059 DOI: 10.1055/s-0031-1298264
Abstract

A new 2-(2-methylpropyl)butanedioic acid derivative, bletillin A ( 1), and a new bibenzyl, bletillin B ( 2), together with seventeen known compounds ( 3- 19), were isolated from the tubers of Bletilla ochracea Schltr. Their structures were established by detailed spectroscopic analyses. Phenanthrenes ( 12- 14) exhibited Antibacterial activities against gram-positive bacteria Staphylococcus aureus, S. epidermidis, and Bacillus subtilis, with MIC values of 12.5-25 µg/mL.

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