Growth hormone receptor and serum binding protein: purification, cloning and expression
- Nature. 1987 Dec;330(6148):537-43. doi: 10.1038/330537a0.
Affiliations
- 1. Department of Developmental Biology, Genentech, Inc., South San Francisco, California.
PMID: 2825030
DOI: 10.1038/330537a0
Abstract
A putative growth hormone receptor from rabbit liver and the growth hormone binding protein from rabbit serum have the same amino-terminal amino-acid sequence, indicating that the binding protein corresponds to the extracellular hormone-binding domain of the liver receptor. The complete amino-acid sequences derived from complementary DNA clones encoding the putative human and rabbit growth hormone receptors are not similar to Other known proteins, demonstrating a new class of transmembrane receptors.