Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3

  • Blood. 2020 Feb 6;135(6):453-456. doi: 10.1182/blood.2019002620.
Chia-Yu Wang  1 ,  Yang Xu  1 ,  Lisa Traeger  2  3 ,  Deniz Y Dogan  2 ,  Xia Xiao  1 ,  Andrea U Steinbicker  2 ,  Jodie L Babitt  1
Affiliations
  • 1. Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
  • 2. Department of Anesthesiology, Intensive Care and Pain Medicine, University of Muenster, Muenster, Germany; and.
  • 3. Anesthesia Center for Critical Care Research of the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
PMID: 31800957 DOI: 10.1182/blood.2019002620